Alcohol Use and Cognitive Functioning Among Middle‐Aged and Older Adults in China: Findings of the China Health and Retirement Longitudinal Study Baseline Survey

Song, Ge; Zhong, Wu; Liu, Tingting; Wang, Jinjiao; Li, Hongjin; Feng, Juan; Li, Changwei

doi:10.1111/acer.13861

Cited by 28 publications

(26 citation statements)

References 37 publications

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“…In accordance with previous studies [ 17 – 19 ], the cognitive performance was tested by two cognition measures in this study: episodic memory and mental intactness. The episodic memory reflects an individual’s ability to immediately repeat ten Chinese words just read to them in any order (referred as immediate recall) and to recall the same words four minutes later (referred as delayed recall).…”

Section: Methodsmentioning

confidence: 93%

High-intensity physical activity is not associated with better cognition in the elder: evidence from the China Health and Retirement Longitudinal Study

Zhang

Miao

et al. 2021

Alz Res Therapy

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Background To evaluate the association of physical activity (PA) intensity with cognitive performance at baseline and during follow-up. Methods A total of 4039 participants aged 45 years or above from the China Health and Retirement Longitudinal Study were enrolled in visit 1 (2011–2012) and followed for cognitive function in visit 2 (2013–2014), visit 3 (2015–2016), and visit 4 (2017–2018). We analyzed the association of PA intensity with global cognition, episodic memory, and mental intactness at baseline using adjusted regression methods and evaluated the long-term effect of PA intensity using multiple measures of cognition scores by mixed effect model. Results In cross-sectional analysis, mild and moderate PA, rather than vigorous PA, was associated with better cognitive performance. The results remained consistent in multiple sensitivity analyses. During the follow-up, participant with mild PA had a 0.56 (95% CI 0.12–0.99) higher global cognition, 0.23 (95% CI 0.01–0.46) higher episodic memory, and 0.33 (95% CI 0.01–0.64) higher mental intactness, while those with moderate PA had a 0.74 (95% CI 0.32–1.17) higher global score, 0.32 (95% CI 0.09–0.54) higher episodic memory, and 0.43 (95% CI 0.12–0.74) higher mental intactness, compared with individuals without PA. Vigorous PA was not beneficial to the long-term cognitive performance. Conclusions Our study indicates that mild and moderate PA could improve cognitive performance, rather than the vigorous activity. The targeted intensity of PA might be more effective to achieve the greatest cognition improvement considering age and depressive status.

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Section: Methodsmentioning

confidence: 93%

High-intensity physical activity is not associated with better cognition in the elder: evidence from the China Health and Retirement Longitudinal Study

Zhang

Miao

et al. 2021

Alz Res Therapy

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“…31 In the CHARLS, about two-thirds of the current drinkers were moderate drinkers (defined as having ≤14 drinks per week), and the remaining were at-risk drinkers (defined as having >14 drinks per week). 32 In the current study, current drinkers had a similar risk of fall as never drinkers. This may be a result of mixture of moderate and at-risk drinking.…”

Section: Discussionmentioning

confidence: 48%

Risk of falls in 4 years of follow-up among Chinese adults with diabetes: findings from the China Health and Retirement Longitudinal Study

et al. 2021

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ObjectivesThis study was to determine the incidence of falls and identify baseline factors increased risk for incident falls over time among people with diabetes.DesignThis study was a secondary analysis using the baseline and 4 years of follow-up data from the China Health and Retirement Longitudinal Study (CHARLS).SettingA nationally representative survey of 17 500 Chinese residents aged 45 years and older were recruited in the baseline national survey in 2011. These participants were followed up every 2 years.ParticipantsA total of 1238 middle-aged and older adults with diabetes and no history of falls at baseline were included in the current study.Primary and secondary outcome measuresInformation on incidence of falls and medical treatment resulting from falls were determined by self-report.ResultsThe findings showed that the incidence of falls was 29.4% during 4 years of follow-up. Participants with incident falls were younger, were more likely to be women, had lower education level and were less likely to be current drinkers. In addition, former drinkers were 2.22 times more likely to fall. Socially active individuals were 47% less likely to fall compared with those without social activities. Every 5 kg increase in grip strength was associated with a 13% lower risk of falls. A 10 mg/dL higher total cholesterol and 1 mg/dL higher blood urea nitrogen were associated with a 4% and 6% higher risk of falls. Finally, participants with depressive symptoms were 1.47 times more likely to fall compared with those without depressive symptoms.ConclusionsThese findings underscore the importance of developing a fall prevention programme for those with diabetes, and this programme should address potentially modifiable risk factors, including levels of total cholesterol, blood urea nitrogen, social activity, depressive symptoms and grip strength.

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“…In accordance with previous studies [17][18][19] , the cognitive performance was tested by two cognition measures in this study: episodic memory and mental intactness. The episodic memory re ects an individual's ability to immediately repeat ten Chinese words just read to them in any order (referred as immediate recall) and to recall the same words four minutes later (referred as delayed recall).…”

Section: Cognition Measurementmentioning

confidence: 91%

High-intensity Physical Activity Is Not Associated With Better Cognition in the Elder: Evidence From the China Health and Retirement Longitudinal Study

Zhang

Miao

et al. 2021

Preprint

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Objective To evaluate the association of physical activity (PA) intensity with cognitive performance at baseline and during follow up. Methods A total of 4 039 participants aged 45 years or above from the China Health and Retirement Longitudinal Study were enrolled in visit 1 (2011-2012), and followed for cognitive function in visit 2 (2013-2014), visit 3 (2015-2016) and visit 4 (2017-2018). We analyzed the association of PA intensity with global cognition, episodic memory and mental intactness at baseline using adjusted regression methods, and evaluated the long-term effect of PA intensity using multiple measures of cognition scores by mixed effect model.Results Compared with individuals without PA, those with mild PA had 0.42 (3.7%) higher global cognition, and 0.20 (5.9%) higher episodic memory, while individuals with moderate PA had 0.59 (5.3%) higher global cognition, 0.25 (7.1%) higher episodic memory, and 0.34 (4.4%) higher mental intactness at baseline. The vigorous PA was not associated with better global cognition, episodic memory and mental intactness (all P>0.05). The results remained almost consistent in multiple sensitivity analyses. In addition, mild and moderate PA, rather than vigorous PA, was beneficial to long-term cognitive performance. Conclusions Our study indicates that mild and moderate PA could improve cognitive performance, rather than the vigorous activity. The targeted intensity of PA might be more effective to achieve the greatest cognition improvement considering age, overweight and depressive status.

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Alcohol Use and Cognitive Functioning Among Middle‐Aged and Older Adults in China: Findings of the China Health and Retirement Longitudinal Study Baseline Survey

Cited by 28 publications

References 37 publications

High-intensity physical activity is not associated with better cognition in the elder: evidence from the China Health and Retirement Longitudinal Study

High-intensity physical activity is not associated with better cognition in the elder: evidence from the China Health and Retirement Longitudinal Study

Risk of falls in 4 years of follow-up among Chinese adults with diabetes: findings from the China Health and Retirement Longitudinal Study

High-intensity Physical Activity Is Not Associated With Better Cognition in the Elder: Evidence From the China Health and Retirement Longitudinal Study

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