Aldehydes, esters, ketones, ethers and amines

Testud, F.; Descotes, Jacques

doi:10.1016/b978-044481557-6/50027-7

Cited by 4 publications

(3 citation statements)

References 38 publications

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“…The bioaccumulation of furfural in other studies was found to be even lethal, or at least be the cause for the genetic degradation and death in rats 42 . Despite the fact that furfural is a natural product from the dehydration of xylose 43 , in fact induces irritations to the human nasal system or even hepatitis due to long term exposure 44 . Recently, the International Agency for Research on Cancer (IARC) has identified both furfural and 2-furanmethanol to be in the group 3 of the classsification (as potent cancer inducing substances), due to the lack of adequate data to support the carcinogenic activity 45 .…”

Section: Resultsmentioning

confidence: 99%

Analysis of volatile emissions from grape berries infected with Aspergillus carbonarius using hyphenated and portable mass spectrometry

Giannoukos¹,

Giannoukos

Lagogianni

et al. 2020

Sci Rep

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Mycotoxins represent a serious risk for human and animal health. Οchratoxin A (OTA) is a carcinogenic mycotoxin produced by A. carbonarius that constitutes a severe problem for viticulture. In this study, we investigate the development of novel detection and on-line monitoring approaches for the detection of OTA in the field (i.e. out of the chemical laboratory) using advanced molecular sensing. Both stand-alone and hyphenated mass spectrometry (MS) based systems (e.g. Time-of-Flight ToF–MS and gas chromatography GC combined with MS) and compact portable membrane inlet MS (MIMS) have been employed for the first time to detect and monitor volatile emissions of grape berries infected by the fungus Aspergillus carbonarius. In vacuo (electron impact—EI) and ambient ionisation (electrospray ionisation—ESI) techniques were also examined. On-line measurements of the volatile emissions of grape berries, infected by various strains of A. carbonarius with different toxicity levels, were performed resulting in different olfactory chemical profiles with a common core of characteristic mass fragments, which could be eventually used for on-site detection and monitoring allowing consequent improvement in food security.

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Section: Resultsmentioning

confidence: 99%

Analysis of volatile emissions from grape berries infected with Aspergillus carbonarius using hyphenated and portable mass spectrometry

Giannoukos¹,

Giannoukos

Lagogianni

et al. 2020

Sci Rep

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“…Hydroformylation of oleic acid (1), especially of different esters, was already studies by many groups [21][22][23][24][25][26][27][28]. Our goal within this project was to apply a readily accessible catalyst like the Rh-TPPTS system in a biphasic reaction approach or other simple ligands such as triphenylphosphine (TPP) in order to form the resulting aldehydes derived from oleic acid (1) being needed for the subsequent steps of our cascade leading to the aminomethyl-substituted fatty acid (5) and isomers thereof.…”

Section: Synthesis Of Branched Bifunctional Molecules Starting From Omentioning

confidence: 99%

Synthesis of Bifunctional Molecules for the Production of Polymers Based on Unsaturated Fatty Acids as Bioderived Raw Materials

Hinzmann

Druhmann

Gröger

2020

Sustainable Chemistry

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Currently, investigations of polymer-building blocks made from biorenewable feedstocks such as, for example, fatty acids, are of high interest for the chemical industry. An alternative synthesis of nitrile-substituted aliphatic carboxylic acids as precursors for ω-amino acids, which are useful to produce polymers, was investigated starting from biorenewable fatty acids. By hydroformylation of unsaturated fatty acids or unsaturated acids being accessible from unsaturated fatty acids by cross-metathesis reactions, aldehydes are formed. In this work, the hydroformylation of such unsaturated acids led to the formation of the corresponding aldehydes, which were afterwards converted with hydroxylamine to aldoximes. Subsequent dehydration by an aldoxime dehydratase as a biocatalyst or by CuII acetate led to the desired nitriles. Within this work, C7-, C9- and C11-carboxylic acids with a terminal nitrile functionality as well as a branched nitrile-functionalized stearate derivative were synthesized by means of this approach. As these nitriles serve as precursors for amino acids being suitable for polymerization, this work represents an alternative synthetic access to polyamide precursors, which starts directly from unsaturated fatty acids as biorenewable resources and avoids harsh reaction conditions as well as and by-product formation.

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“…Antimicrobial action of aldehydes seems to be mainly located in the cell surface due to a disturbance of membrane proteins functions [9,10]. The biocidal activity of aldehydes decreases with the carbon chain length and also depends on the presence or absence of unsaturated links, being the unsaturated aldehyde more active than the saturated homolog [11]. The median lethal dose (LD 50 ) for GA in rats is 2 g kg −1 and is considered as slightly to moderately toxic [12].…”

Section: Introductionmentioning

confidence: 99%