Algorithm for Establishing Lifetime of Strangulation Mechanical Asphyxiation

Abstract

1 1 ФГБУ «Российский центр судебно-медицинской экспертизы» Минздрава России, Москва 2 Кафедра судебной медицины ФГБОУ ВО «Астраханский государственный медицинский университет» Минздрава России, Астрахань 3 БУ «Республиканское бюро судебно-медицинской экспертизы» Минздрава Чувашии, Чебоксары Аннотация: Методы иммуногистохимии имеют большое значение в морфологии, а именно в судебно-ме-дицинской гистологии. Были исследованы 19 наблюдений стангуляционной механической асфиксии в воз-растной группе от 28 до 48 лет. Для сравнения изучены 3 наблюдения механической асфиксии в результате утопления в возрастной группе от 35 до 50 лет. Контрольная группа составила 11 наблюдений острой фор-мы ишемической болезни сердца, 6 наблюдений смерти от травматического шока. В процессе исследования фибриноген может быть оценен как субстанция раннего реагирования на повреждение и маркер прижизнен-ности странгуляционной механической асфиксии. Данный алгоритм может быть предложен для диагностики странгуляционной асфиксии. Ключевые слова: асфиксия, прижизненность, иммуногистохимия, CD-117 ALGORITHM FOR ESTABLISHING LIFETIME OF STRANGULATION MECHANICAL ASPHYXIATIOND. V. Bogomolov, Yu. V. Zbrueva, G. G. Semenov, O. P. Denisova Abstract: Methods of immunohistochemistry are of great importance in morphology, namely in forensic histology. 19 observations of statutory mechanical asphyxia were studied in the age group from 28 to 48 years. For comparison, 3 observations of mechanical asphyxia as a result of drowning in the age group from 35 to 50 years have been studied. The control group consisted of 11 observations of the acute form of coronary heart disease, 6 cases of death from traumatic shock. In the process of research, fibrinogen can be evaluated as the substance of early response to damage and the marker of intactness of strangulation mechanical asphyxia. This algorithm can be proposed for the diagnosis of strangulation asphyxia.

Diagnostics of mechanical asphyxia – experience of foreign countries (literature review)

“…Thus, according to the classification of D. V. Bogomolov and co-authors [6], the first morphological reactive changes at the microscopic level, such as arterial spasm; plethora of arteries, veins, capillaries; fibrin loss; marginal standing of leukocytes can be detected at least 5-10 minutes after the action of a mechanical stimulus. At the same time, for the development of such phenomena as connective or nervous tissue edema, hemolysis of erythrocytes in hemorrhages, an increase in the number of neutrophils in the lumens of blood vessels, the appearance of the first macrophages requires from 30 minutes.…”

Forensic Medical Assessment of Thanatogenesis in the Experience of Gunshot Injuries

“…During the examination of a gunshot injury, it is necessary to answer the investigator's questions about the cause of death, the type and rate of thanatogenesis, the distance of the shot, the sequence and mechanism of damage formation, and the severity of the injury 4,6,7,8,9 .…”