Algorithm for the diagnosis of smear‐negative pulmonary tuberculosis in high‐incidence resource‐constrained settings

Soto, Alonso; Solari, Lely; Agapito, Juan; Gotuzzo, Eduardo; Accinelli, Roberto A.; Vargas, Dante; Acurio, Vilma; Matthys, Francine; Stuyft, Patrick Van der

doi:10.1111/tmi.12172

Cited by 7 publications

(3 citation statements)

References 26 publications

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“…The purified protein derivative test, however, is of little or no value in the diagnosis of active pulmonary tuberculosis, especially in elderly and immunosuppressed patients [3,4]. Smearnegative active pulmonary tuberculosis is a serious disease, which is particularly the case in immunosuppressed situations [5]. Conventional radiographs can also have atypical or unremarkable findings, particularly in elderly patients and in chronic cases because of scars from previous pulmonary tuberculosis [6,7].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic utility of 99mTc-EDDA-tricine-HYNIC-Tyr3-octreotate SPECT for differentiation of active from inactive pulmonary tuberculosis

Ahmadihosseini

Abedi

Rad

et al. 2014

Nuclear Medicine Communications

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Section: Introductionmentioning

confidence: 99%

Diagnostic utility of 99mTc-EDDA-tricine-HYNIC-Tyr3-octreotate SPECT for differentiation of active from inactive pulmonary tuberculosis

Ahmadihosseini

Abedi

Rad

et al. 2014

Nuclear Medicine Communications

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“…This will enable timely interventions to relieve negative emotions and enhance the patient's confidence in managing the disease. Additionally, trust and cooperation from the patient's family should also be encouraged (12)(13)(14)(15). Health education on pulmonary tuberculosis was provided for patients and their families through group information sessions, individual guidance, one-to-one questions and answers, etc.…”

Section: Study Methodsmentioning

confidence: 99%

Effects of comprehensive nursing intervention combined with respiratory functional exercises on pulmonary function and self-care ability in patients with pulmonary tuberculosis: results of a randomized trial

Xu¹,

Chen²,

Li³

2021

Ann Palliat Med

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Background: This study was carried out based on the background that pulmonary tuberculosis seriously threatens people's physical health while the current treatment has certain limitations.Methods: A total of 150 patients with pulmonary tuberculosis who were admitted to Wuhan Jinyintan Hospital from January 2017 to December 2018 were selected as study participants. Patients were randomly divided into a control group (n=75) who were treated with routine nursing, and an experimental group (n=75) who were treated with comprehensive nursing intervention combined with respiratory functional exercises.Following treatment, the pulmonary function, self-care ability, and other indexes of the patients in both groups were compared and analyzed.Results: After nursing intervention, the pulmonary function and self-care ability of patients in the experimental group were significantly higher than those in the control group. The scores of the 6-minute walking distance (6MWD) and modified Medical Research Council (mMRC) dyspnea scale of patients in both groups were significantly higher after nursing intervention compared to before intervention. Furthermore, after intervention, the scores in the experimental group were significantly higher than those in the control group. The partial pressure of oxygen (PaO 2 ), partial pressure of carbon dioxide (PaCO 2 ), and the quality of life of patients in the experimental group after intervention were significantly better than those in the control group.Conclusions: Comprehensive nursing intervention combined with respiratory functional exercises can significantly improve the pulmonary function, self-care ability, and quality of life of patients with pulmonary tuberculosis, with obvious clinical efficacy.

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“…En el abanico de la búsqueda de TBC ahora disponemos de la biología molecular, que entrega una sensibilidad mejor que la baciloscopía y similar al cultivo de Koch, con la diferencia de sus rápidos resultados y de la entrega de susceptibilidad a fármacos, habitualmente a la R. Junto a esto, existe una mayor utilización de recursos imagenológicos, procedimientos (lavado broncoalveolar, biopsias, punciones, etc.) que pueden combinarse con la biología molecular 21,22,23,24,25,26,27,28,29 .…”

Section: Letalidad De La Tbcunclassified

Eficiencia del tratamiento de casos nuevos de tuberculosis sensible en Chile

2021

Rev. chil. enferm. respir.

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Treatment efficiency in new cases of susceptible tuberculosis in ChileTuberculosis therapy with the primary regimen recommended by the World Health Organization does not cure all cases globally, but it reached success in at least 85% of cases in the year 2018. The same year in Chile, treatment efficiency is achieved in only 76%, mainly due to the high proportion of deaths and loss of follow-up during therapy. Preliminary data show that in the 2019 cohort the success was achieved only in about 74% of new cases. Treatment failures in Chile are rare due to national surveillance of drug susceptibility. To reduce fatality, it is necessary to reinforce the strategies for early diagnosis of tuberculosis through new algorithms. Such strategies should include molecular biology and radiology in suspected TB cases, to promote proper management of comorbidities, establish an adequate social support network and have centers available for prolonged hospitalization when needed. In addition, patient's adherence to therapy should be strengthened with strategies that encourage and facilitate attendance.

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Algorithm for the diagnosis of smear‐negative pulmonary tuberculosis in high‐incidence resource‐constrained settings

Abstract: Abstractobjectives Diagnosis of smear-negative pulmonary tuberculosis (SNPT) remains a challenge, particularly in resource-constrained settings. We evaluated a diagnostic algorithm that combines affordable laboratory tools and a clinical prediction rule (CPR).

Cited by 7 publications

References 26 publications

Diagnostic utility of 99mTc-EDDA-tricine-HYNIC-Tyr3-octreotate SPECT for differentiation of active from inactive pulmonary tuberculosis

Diagnostic utility of 99mTc-EDDA-tricine-HYNIC-Tyr3-octreotate SPECT for differentiation of active from inactive pulmonary tuberculosis

Effects of comprehensive nursing intervention combined with respiratory functional exercises on pulmonary function and self-care ability in patients with pulmonary tuberculosis: results of a randomized trial

Eficiencia del tratamiento de casos nuevos de tuberculosis sensible en Chile

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