Alk-1-enyl ether phospholipids (plasmalogens) and glycolipids of Treponema hyodysenteriae

Matthews, Herbert M.; Yang, Tao; Jenkin, Howard M.

doi:10.1016/0005-2760(80)90033-8

Cited by 21 publications

(26 citation statements)

References 41 publications

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“…Similarly, PG is a phospholipid that is scarce in most mammalian tissues, however, is relatively abundant in bacterial membranes, including those of treponemes (29,(45)(46)(47). CL is also present in the membrane of several bacteria, such as T. pallidum (29).…”

Section: Discussionmentioning

confidence: 99%

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Treponemal Phospholipids Inhibit Innate Immune Responses Induced by Pathogen-associated Molecular Patterns

Hashimoto¹,

Asai²,

Ogawa

2003

Journal of Biological Chemistry

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Section: Discussionmentioning

confidence: 99%

“…1a). (45)(46)(47) indicated that Fr. a-e corresponded to neutral lipid, sterols, galactosylglycerolipid, PG, and PC, respectively.…”

Section: Treponemal Phospholipid Inhibits Lps-inducedmentioning

confidence: 99%

Treponemal Phospholipids Inhibit Innate Immune Responses Induced by Pathogen-associated Molecular Patterns

Hashimoto¹,

Asai²,

Ogawa

2003

Journal of Biological Chemistry

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“…The quantities of alkenyl ether lipids in the lipid extracts were estimated from the average chain lengths and the relative amounts of the acyl and alkenyl moieties (24), as determined by gas-liquid chromatography. Since the other three major alkenyl components did not cochromatograph with any fatty acid from any of the 21 strains, the profiles of the combined esterified fatty acid and alkenyl moieties were also determined for each strain without prior separation of the two groups by thin-layer chromatography (Table 1).…”

Section: Methodsmentioning

confidence: 99%

“…Lipid constituents were identified and quantified by using authentic reference and internal standards as previously described (23,24) and by comparison with previously characterized lipids and lipid derivatives from the type strains (24,25). The quantities of alkenyl ether lipids in the lipid extracts were estimated from the average chain lengths and the relative amounts of the acyl and alkenyl moieties (24), as determined by gas-liquid chromatography.…”

Section: Methodsmentioning

confidence: 99%

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Cellular Lipid Comparisons Between Strains of Treponema hyodysenteriae and Treponema innocens

Matthews

Kinyon

1984

International Journal of Systematic Bacteriology

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The cellular lipids of 11 strains of Treponemu hyodysenteriae and 10 strains of non-enteropathogenic, weakly beta-hemolytic spirochetes classified as Treponema innocens were extracted with chloroformmethanol and analyzed by thin-layer and gas-liquid chromatography for fatty acids, alkenyl moieties, alkenyl ether lipid compositions, monoglycosyldiglyceride, acylmonoglycosyldiglyceride, and the types of sugars in the glycolipids. Most strains were distinguishable at the species level on the basis of the ratio of 14:O to is0-15:O alkenyl moieties; 14:O moieties predominated in most T. hyodysenteriae strains, whereas most strains classified as T. innocens contained more is0-15:O moieties. The other aspects of lipid composition were not useful for differentiation. All of the strains had similar cellular fatty acid profiles and contained monoglycosyldiglyceride. The mean alkenyl ether lipid compositions were 48 and 32% of the total lipids of strains of T. hyodysenteriae and T. innocens, respectively. Galactose was the predominant sugar in the glycolipids of 18 strains, 17 of which also contained acylmonoglycosyldiglyceride. Three strains classified as T. innocens contained primarily glucose in their glycolipids and did not contain acylmonoglycosyldiglyceride. Gas-liquid chromatographic determinations of the alkenyl chain profiles of the extractable cellular lipids provided useful information for differentiation of the etiological agent of swine dysentery from morphologically similar, nonpathogenic spirochetes.

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B rachyspira

Looft¹,

Stanton²

2018

Bergey's Manual of Systematics of Archaea and Bacteria

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Bra.chy.spi'ra. (Gr. adj. brachys , short; Gr. n. spira , a coil, helix; N.L. fem. n. Brachyspira , describing a bacterium that resembles a short helix). Spirochaetes / Spirochaetia / Spirochaetales / Brachyspiraceae / Brachyspira The genus Brachyspira consists of obligately anaerobic, aerotolerant spirochetes, which inhabit the intestinal tracts of birds and mammals, including humans. They have been found globally in free‐living birds. The type species of the genus is Brachyspira aalborgi . There are numerous yet‐to‐be characterized brachyspire species. Brachyspires have fastidious growth requirements requiring chemically complex culture media supplemented with blood or serum. The best studied species, Brachyspira hyodysenteriae, requires cholesterol and phospholipid for growth. The brachyspires are chemoorganotrophic, using various simple carbohydrates for growth. Metabolic products are acetate, butyrate, H 2 , and CO 2 . Brachyspira spp. use NADH oxidase as defense against oxygen exposure. Species are differentiated by 16S rRNA gene sequences and genome DNA homology comparisons (chemical and digital). Genome sequences of the type strains of every species except B. aalborgi are publicly available. There are nine Brachyspira species, of which eight are considered enteropathogenic for their host animal. Diseases associated with the brachyspires include swine dysentery, spirochetal colitis, and intestinal spirochetosis. Dysenteric species ( Brachyspira hyodysenteriae , Brachyspira suanatina , and Brachyspira hampsonii ) form strongly hemolytic (i.e., beta hemolytic) colonies on trypticase soy blood agar. Other species are “weakly” hemolytic. B. hyodysenteriae cells exchange chromosomal genes via VSH‐1, a novel GTA (gene transfer agent). MLST (multiple locus sequence typing) analyses have been applied to investigate B. hyodysenteriae and Brachyspira pilosicoli epidemiology and to interpret species evolution. A database of STs (MLST sequence types) for B. hyodysenteriae strains has been established. DNA G + C content (mol%) : 24.6–27.5 ( T m ; genome sequence). Type species : Brachyspira aalborgi Hovind‐Hougen, Birch‐Andersen, Henrik‐Nielsen, Orholm, Pedersen, Teglbjaerg and Thaysen 1983, 896 VP (Effective publication: Hovind‐Hougen, Birch‐Andersen, Henrik‐Nielsen, Orholm, Pedersen, Teglbjaerg and Thaysen 1982, 1135).

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Alk-1-enyl ether phospholipids (plasmalogens) and glycolipids of Treponema hyodysenteriae

Cited by 21 publications

References 41 publications

Treponemal Phospholipids Inhibit Innate Immune Responses Induced by Pathogen-associated Molecular Patterns

Treponemal Phospholipids Inhibit Innate Immune Responses Induced by Pathogen-associated Molecular Patterns

Cellular Lipid Comparisons Between Strains of Treponema hyodysenteriae and Treponema innocens

B rachyspira

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