1995
DOI: 10.1016/0031-9422(95)00192-a
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Alkaloids from Dactylicapnos torulosa

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Cited by 58 publications
(37 citation statements)
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“…Compounds 1-4 were identified to be 8-hydroxydihydrochelerythrine, 14) 8-hydroxydihydrosanguinarine, 15) noroxyhydrastinine, 16) and berberine, 17) respectively, which mass and NMR spectral data Vol. 29, No.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Compounds 1-4 were identified to be 8-hydroxydihydrochelerythrine, 14) 8-hydroxydihydrosanguinarine, 15) noroxyhydrastinine, 16) and berberine, 17) respectively, which mass and NMR spectral data Vol. 29, No.…”
Section: Resultsmentioning
confidence: 99%
“…19) The optical rotation of compounds 1 [ϩ8.5°(cϭ0.1, MeOH)] and 2 [Ϫ2.5°(cϭ0.16, MeOH)] suggested that they are probably unequal mixtures of enantiomers like the reported 8-hydroxydihydrosanguinarine [Ϫ9°(cϭ0.4, MeOH)]. 15) The AChE inhibitory activities of compounds 1-4 were determined using Ellman's coupled enzyme assay. As shown in Fig.…”
Section: Resultsmentioning
confidence: 99%
“…The H-2 and H-3 was confirmed as cis-and axial orientations by a comparison of coupling constant between H-2 and H-3 (J = 8.5 Hz), and the observed NOE correlations. 11 In the NOESY spectrum, the cross peak was detected between H-3 and H-1', which is clearly indicated the relative configuration of C-α as shown in Figure 3. However, the optical rotation showed a zero value, it may be a racemate.…”
mentioning
confidence: 83%
“…11 The skeleton of rearranged phthalideisoquinoline alkaloid, consists of unique ring C, D with C-N-O-C, moieties, and the lactone ring E, was further clarified with H COSY data. Moreover, the A-E ring system was assigned by the observed HMBC correlations from H-1 (δ H 3.05, 2.88) to C-2, C-7, C-3a and C-7a, from H-3 (δ H 4.62) to C3a and C-6', and from H-1' (δ H 7.42) to C-α.…”
mentioning
confidence: 99%
“…Phytochemical studies have led to the isolation of many alkaloids from about half of the 18 species (Yakhontova, Komarova, Perel'son, Blinova, & Tolkachev, 1972;Hussain, GoÈ zler, Shamma, & GoÈ zler, 1982;Yakhontova, Tolkachev, Komarova, & Shreter, 1984;Ta borska , VeÏ znõ k, Slavõ k, Sedmera, & Sima nek, 1988;Saad, 1995). In previous investigations of H. leptocarpum some alkaloids belonging to the benzo[c]phenanthridine, isoquinoline and spiroisoquinoline types were identi®ed (Chen & Fang, 1985;Slavõ k & Slavõ kova, 1961;Zhang, RuÈ cker, Breitmaier, & Mayer, 1995). In this reinvestigation of this plant ®ve new alkaloids leptocarpinine (1), leptopine (2), leptopinine (3), leptopidine (4) and leptopidinine (5), together with protopine (6), isohyperectine (7) and oxohydrastinine (8), were isolated.…”
Section: Introductionmentioning
confidence: 99%