Alkaloids of Buxus colchica, B. sempervirens, and B. balearica growing in Georgia

Vachnadze, N; Vachnadze, V. Yu.; Jakeli, Eteri; Tsakadze, D. M.

doi:10.1007/s10600-010-9465-0

Cited by 3 publications

(4 citation statements)

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“…39 The assay was carried out at room temperature in 100 mM sodium phosphate buffer at pH 7.8. In a typical assay, 126 µL of buffer, 50 µL of 0.01 M DTNB [5,5′-dithiobis(2-nitrobenzoic acid)], 2 µL of enzyme, and 2 µL of solutions containing test compounds (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12) were mixed and incubated for 30 min. The reaction was then initiated by the addition of 20 µL of 0.075 M acetylthiocholine.…”

Section: Methodsmentioning

confidence: 99%

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confidence: 99%

“…The genus Buxus is a rich source of alkaloids comprised of a steroid-triterpenoid pregnane-type 9β,10β-cycloartenol system (with C-4 methyls) and a degraded C-20 side chain. [1][2][3][4] Phytochemical studies on various plants of this genus, including Buxus semper-Virens, B. papillosa, B. microphylla,, B. hildebrandtii, and B. hyrcana, resulted in the isolation of over 200 triterpenoidal alkaloids. Some of these alkaloids have been reported to exhibit antimalaria, antituberculosis, anti-HIV, and anticancer activities and have been used to treat skin infections, rheumatism, and heart disorders.…”

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Triterpenoidal Alkaloids from Buxus natalensis and Their Acetylcholinesterase Inhibitory Activity

et al. 2010

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Acetylcholinesterase (AChE) inhibition-directed phytochemical studies on the methanolic extract of Buxus natalensis, collected in South Africa, resulted in the isolation of 12 compounds: O(2)-natafuranamine (1), O(10)-natafuranamine (2), cyclonataminol (3), 31-demethylbuxaminol A (4), buxaminol A (5), buxafuranamide (6), buxalongifolamidine (7), buxamine A (8), cyclobuxophylline K (9), buxaminol C (10), methyl syringate (11), and p-coumaroylputrescine (12). Compounds 1-4 were new alkaloids, and compound 5 was isolated for the first time as a natural product. Their structures were elucidated with the aid of extensive NMR and mass spectroscopic studies. Compounds 1 and 2 are members of a rarely occurring class of Buxus alkaloids, having a tetrahydrofuran ring incorporated in their structures. Compounds 1-12 exhibited strong to moderate AChE inhibitory activity.

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Triterpenoidal Alkaloids from Buxus natalensis and Their Acetylcholinesterase Inhibitory Activity

et al. 2010

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“…Feeding larvae need to be physiologically capable of digesting host tissues and dealing with any allelochemicals present. Studies investigating the composition of secondary compounds in leaves and other plant organs of box-trees revealed that alkaloids accumulate especially during the fruiting phase in summer (Vachnadze et al 2009). Larvae of different seasonal generations are therefore exposed to different concentrations of alkaloids.…”

Section: Larval Performance On Different Box-tree Varietiesmentioning

confidence: 99%

Oviposition preference and larval development of the invasive moth Cydalima perspectalis on five European box‐tree varieties

Leuthardt

Baur

2012

J Applied Entomology

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The box‐tree pyralid Cydalima perspectalis (Walker 1859) (Lepidoptera: Pyralidae), native to Eastern Asia, is a newly introduced species causing severe damage to box‐trees (Buxus sp.) in private and public gardens as well as in semi‐natural box‐tree forests in Central Europe. It is so far not known whether different box‐tree subspecies (or varieties) are similarly affected by this invasive moth. In a choice experiment offering branches of five different box‐tree varieties as oviposition sites, we found a preference of female moths for laying their egg clusters on the variety ‘Rotundifolia’, while other varieties were less frequently considered. The preference for ‘Rotundifolia’, the variety with the largest leaves in the tests, remained when intervariety differences in foliar area (mean leaf size × number of leaves) were taken into account. Feeding larvae on leaves of either of the five box‐tree varieties revealed a significant effect of the seasonal generation of C. perspectalis on the growth rate of individuals but no influence of the box‐tree variety. Larvae from the spring generation show the highest growth rate, those from the summer generation a moderate and those from the autumn generation the lowest growth rate. The moths used in the experiments may belong to the 10th to 12th generation present in Europe. The time elapsed since their introduction may be too short for an optimal adaptation to the partly novel diet encountered by the invasive moth.

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Identifying the ecological and societal consequences of a decline in Buxus forests in Europe and the Caucasus

Mitchell

Chitanava²,

Дбар³

et al. 2018

Biol Invasions

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Alkaloids of Buxus colchica, B. sempervirens, and B. balearica growing in Georgia

Cited by 3 publications

References 4 publications

Triterpenoidal Alkaloids from Buxus natalensis and Their Acetylcholinesterase Inhibitory Activity

Triterpenoidal Alkaloids from Buxus natalensis and Their Acetylcholinesterase Inhibitory Activity

Oviposition preference and larval development of the invasive moth Cydalima perspectalis on five European box‐tree varieties

Identifying the ecological and societal consequences of a decline in Buxus forests in Europe and the Caucasus

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