2021
DOI: 10.29024/jsim.105
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All Sugars are Not Sweet

Abstract: Background: Extravasation is defined as the leakage of drugs from the vessel to the surrounding area with the potential to cause tissue necrosis. Such drugs (known as vesicants) that can extravasate include vasopressors, alkylating chemotherapeutic agents, hyperosmolar or hypo-osmolar agents, and certain antibiotics (vancomycin) [1]. Dextrose, at concentrations of 10% or greater, is also considered to be a vesicant, with rates of extravasation from 50% dextrose (D50) injections varying between 10-30% [2]. Case… Show more

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