2020
DOI: 10.21203/rs.3.rs-100922/v1
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Allele Frequency Analysis Suggests Potentially Protective Effect in the Lithuanian Population

Abstract: Background. In the scientific literature, a wide range of effect variants that protect against complex disease phenotypes has been identified. Analysis of these variants and overall genetic structure of isolated or, in our case, small populations is important in association analysis. When analysing admixture populations during GWAS, one could expect inaccuracies, which could be eliminated by choosing distinct populations as one of the interests of study. Population genetic structure determines similarities and… Show more

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