2020
DOI: 10.1097/aci.0000000000000675
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Allergic conjunctivitis in children: current understanding and future perspectives

Abstract: Purpose of review The rising global burden of allergic diseases, particularly in the pediatric population, is of serious concern. Ocular allergy is one of the most common ocular pathologies met in clinical practice. A large proportion of children and adolescents suffer from allergic eye diseases (AEDs), which affect their quality of life. The available treatments and surgical modalities have their limitations and side effects. Therefore, the development of novel and alternate strategies is the need… Show more

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Cited by 19 publications
(17 citation statements)
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“…A few pediatric QOL questionnaires looking at vernal keratoconjunctivitis, a more severe and difficult-to-treat form of AC, have been developed and reported, but have not included parental QOL questionnaires. 4 Zhang et al 1 therefore chose to use the general health-related QOL questionnaire, Pediatric Quality of Life Inventory, version 4.0, to assess QOL of children and their parents; the questionnaire includes the age-specific Child-Self-report for children, and the Family Impact Module for parents. This study is unique in reporting QOL data for the parents of the children respondents.…”
Section: Limitationsmentioning
confidence: 99%
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“…A few pediatric QOL questionnaires looking at vernal keratoconjunctivitis, a more severe and difficult-to-treat form of AC, have been developed and reported, but have not included parental QOL questionnaires. 4 Zhang et al 1 therefore chose to use the general health-related QOL questionnaire, Pediatric Quality of Life Inventory, version 4.0, to assess QOL of children and their parents; the questionnaire includes the age-specific Child-Self-report for children, and the Family Impact Module for parents. This study is unique in reporting QOL data for the parents of the children respondents.…”
Section: Limitationsmentioning
confidence: 99%
“…Furthermore, the World Health Organization has emphasized that health care for individuals with chronic conditions should be reoriented to focus on the patients and their families . Allergy is a common chronic condition with a substantially increasing worldwide prevalence . This condition has become a major public health issue that negatively affects the quality of life (QOL) and generates significant social expense as reported by the World Allergy Organization .…”
Section: Introductionmentioning
confidence: 99%
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“…Allergic conjunctivitis (AC) is one of the most common ocular disorders in clinical practice [ 1 ], with a 28% incidence in China [ 2 ], a nearly 25% incidence in children in Europe [ 3 ], and between 20% and 30% incidence in the United States [ 4 ]. The major symptoms of AC are itching, swelling, and tearing, and in some severe cases, photophobia and pain could develop due to the involvement of the cornea [ 5 , 6 ]. Patients suffering from AC have a lower health-related quality of life and impaired socioeconomic status [ 7 , 8 , 9 , 10 ].…”
Section: Introductionmentioning
confidence: 99%
“…At present, there are multiple clinical treatment methods for AC, among which, western medicine mostly employs antihistamines, short-term corticosteroids, mast cell stabilizers, and subcutaneous or sublingual immunotherapy (5,7,8). For patients with severe AC, immunosuppressants such as cyclosporine eye drops are also applied (9). However, these therapies are largely based on symptomatic relief.…”
Section: Introductionmentioning
confidence: 99%