2018
DOI: 10.1111/cod.13024
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Allergic contact dermatitis caused by octylisothiazolinone in a leather sofa

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Cited by 12 publications
(10 citation statements)
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“…More recently, Vandevenne et al described methylisothiazolinone, present in leather care products for sofas, as the responsible allergen in a case of severe ACD mainly located on the posterior sides of the thighs. Moreover, other isothiazolinone derivatives, such as octylisothiazolinone, have also been implicated as responsible allergens in leather goods, that is, sofas, belts, and shoes . The GC‐MS analysis of the belt from case 1 showed the probable presence of octylisothiazolinone, but the patient did not react positively to it.…”
Section: Discussionmentioning
confidence: 99%
“…More recently, Vandevenne et al described methylisothiazolinone, present in leather care products for sofas, as the responsible allergen in a case of severe ACD mainly located on the posterior sides of the thighs. Moreover, other isothiazolinone derivatives, such as octylisothiazolinone, have also been implicated as responsible allergens in leather goods, that is, sofas, belts, and shoes . The GC‐MS analysis of the belt from case 1 showed the probable presence of octylisothiazolinone, but the patient did not react positively to it.…”
Section: Discussionmentioning
confidence: 99%
“…It is predominantly an occupational allergen, but non‐occupational ACD has recently been described to leather goods with 11 previously reported patients (Table 1). In three cases, sofas were implicated (one patient additionally to a car seat), 2‐4 and in two cases chairs 3,5 . Six of the eleven patients had ACD from shoes or sandals, 2,6 two to watch straps, 2 and one to a belt 2 .…”
Section: Discussionmentioning
confidence: 99%
“…Briefly, 0.5 g of nitrile was dissolved in 5 ml of methanol, sonicated during 15 min, and centrifuged during 10 min at 3500 RCF. After filtration, the extract was analysed by high pressure liquid chromatography coupled to a diode array detector following a previously published procedure 2 …”
Section: Case Reportmentioning
confidence: 99%