Allergic contact dermatitis due to diisopropyl sebacate

Dooms‐Goossens, A.; Veylder, H. De; Boulle, Koenraad De; Maertens, Michiel

doi:10.1111/j.1600-0536.1986.tb01329.x

Cited by 7 publications

(4 citation statements)

References 1 publication

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“…Two case studies were reported of allergic reactions to lotion containing diisopropyl sebacate. 159,160…”

Section: Toxicologic Studiesmentioning

confidence: 99%

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Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Dicarboxylic Acids, Salts, and Esters

Fiume¹,

Eldreth²,

Bergfeld³

et al. 2012

Int J Toxicol

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The CIR Expert Panel assessed the safety of dicarboxylic acids and their salts and esters as used in cosmetics. Most dicarboxylic acids function in cosmetics as pH adjusters or fragrance ingredients, but the functions of most of the salts in cosmetics are not reported. Some of the esters function as skin conditioning or fragrance ingredients, plasticizers, solvents, or emollients. The Expert Panel noted gaps in the available safety data for some of the dicarboxylic acid and their salts and esters in this safety assessment. The available data on many of the ingredients are sufficient, however, and similar structural activity relationships, biologic functions, and cosmetic product usage suggest that the available data may be extrapolated to support the safety of the entire group. The Panel concluded that the ingredients named in this report are safe in the present practices of use and concentration.

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“…Two case studies were reported of allergic reactions to lotion containing diisopropyl sebacate. 159,160…”

Section: Toxicologic Studiesmentioning

confidence: 99%

“…Two case studies were reported of allergic reactions to lotion containing diisopropyl sebacate. 159,160 Diethylhexyl Sebacate Nonhuman. The dermal irritation potential of diethylhexyl sebacate was evaluated using the same procedure.…”

Section: Smentioning

confidence: 99%

Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Dicarboxylic Acids, Salts, and Esters

Fiume¹,

Eldreth²,

Bergfeld³

et al. 2012

Int J Toxicol

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show abstract

“…No cross‐reactions have been reported so far, although adipic acid – once reported as a contact allergen in a polyester‐exposed machine repairman (4)– can be used as an intermediate in the synthesis of sebacate (4). Several cases of sensitization to the latter have been reported, mainly in antimycotic ointments and, more recently, in certain cosmetics, including lipsticks and hand creams (5–9).…”

Section: Discussionmentioning

confidence: 99%

Bis-diglycerylpolyacyladipate-2: An emergent allergen in cosmetics?

2011

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“…Examples include fatty acids, for example the sebacate family (e.g. 3), fatty acid esters such as isopropyl myristate (e.g. 4), benzethonium, and benzalkonium chloride (e.g.…”

mentioning

confidence: 99%