Allergic Contact Dermatitis from Carmine

Shaw, Daniel W.

doi:10.2310/6620.2009.09025

Cited by 39 publications

(16 citation statements)

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“…The CC38K sequence showed homology to phospholipases, which are known to be allergens in other insects. Although there are numerous case reports of type I hypersensitivity reactions to carmine in the literature, only four cases of allergic contact dermatitis have been reported (19,20). There is no study or case report of the relationship between carmine and AE.…”

Section: Discussionmentioning

confidence: 99%

Is Patch Testing with Food Additives Useful in Children with Atopic Eczema?

Çatlı¹,

Bostancı

Özmen

et al. 2015

Pediatric Dermatology

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Section: Discussionmentioning

confidence: 99%

Is Patch Testing with Food Additives Useful in Children with Atopic Eczema?

Çatlı¹,

Bostancı

Özmen

et al. 2015

Pediatric Dermatology

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“…Biologically active anthraquinone derivatives have also been identified in bacteria, fungi, and insects . Both natural and synthetic anthraquinones are widely used in textile dying, paints, imaging devices, foods, cosmetics, and pharmaceuticals . Moreover, they serve as catalysts in many chemical and biogeochemical processes, such as reductive degradation of contaminants, based on their redox potential …”

Section: Introductionmentioning

confidence: 99%

“…12 Both natural and synthetic anthraquinones are widely used in textile dying, paints, imaging devices, foods, cosmetics, and pharmaceuticals. [13][14][15][16][17][18][19][20][21][22] Moreover, they serve as catalysts in many chemical and biogeochemical processes, such as reductive degradation of contaminants, based on their redox potential. 23,24…”

Section: Introductionmentioning

confidence: 99%

Anthraquinones As Pharmacological Tools and Drugs

Malik

Müller

2016

Medicinal Research Reviews

355

211

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Anthraquinones (9,10-dioxoanthracenes) constitute an important class of natural and synthetic compounds with a wide range of applications. Besides their utilization as colorants, anthraquinone derivatives have been used since centuries for medical applications, for example, as laxatives and antimicrobial and antiinflammatory agents. Current therapeutic indications include constipation, arthritis, multiple sclerosis, and cancer. Moreover, biologically active anthraquinones derived from Reactive Blue 2 have been utilized as valuable tool compounds for biochemical and pharmacological studies. They may serve as lead structures for the development of future drugs. However, the presence of the quinone moiety in the structure of anthraquinones raises safety concerns, and anthraquinone laxatives have therefore been under critical reassessment. This review article provides an overview of the chemistry, biology, and toxicology of anthraquinones focusing on their application as drugs.

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“…Należy rozróżnić E120 od czerwonych azowych barwników syntetycznych, takich jak ponceau 4R (cochineal red A, E124, CI 16255), allura red AC (E129, CI 16035), należących do tzw. uwalniaczy histaminy, które nie biorą udziału w reakcjach związanych z IgE [6,19].…”

Section: Charakterystyka Karminuunclassified

“…Zawiera go też pasta do zębów Biomed sensitive. Może być również używany w produkcji farb, tkanin lub tuszu [19].…”

Section: źRódła Karminuunclassified

Carmine – overlooked allergen in diagnostic of immediate and delayed idiopathic hypersensitivity

Sadowska¹,

Chełmińska²

2019

pja

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Karmin (E120, Natural Red 4, color index no. 75470) jest naturalnym czerwonym barwnikiem uzyskiwanym z wysuszonych ciał insektów Dactylopius coccus płci żeńskiej, powszechnie stosowanym w przemyśle spożywczym, kosmetycznym i farmaceutycznym. Zanieczyszczenia białkowe w karminie pochodzące z owadów mogą odpowiadać za reakcje alergiczne. Zarejestrowano ponad 80 przypadków nadwrażliwości po spożyciu, inhalacji lub kontakcie z karminem. Reakcje anafilaktyczne, pokrzywka i alergia kontaktowa zdarzały się głównie u pacjentek z atopią, podczas gdy astmę zawodową diagnozowano w większości u chorych płci męskiej po przedłużonej ekspozycji na E120. Reakcje nadwrażliwości zależne od IgE mogą pojawić się natychmiast lub nawet po kilku godzinach od spożycia karminu. Punktowe testy skórne z karminem są dodatnie u ok. 3% pacjentów diagnozowanych z powodu alergii pokarmowej i jest to prosta metoda przesiewowa na E120. W ocenie nadwrażliwości wykorzystuje się pomiar miana przeciwciał sIgE, test aktywacji bazofilów, testy płatkowe oraz prowokację doustną lub inhalacyjną. Obecnie nie są dostępne europejskie standardy postępowania w nadwrażliwości na karmin.

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Allergic Contact Dermatitis from Carmine

Cited by 39 publications

References 0 publications

Is Patch Testing with Food Additives Useful in Children with Atopic Eczema?

Is Patch Testing with Food Additives Useful in Children with Atopic Eczema?

Anthraquinones As Pharmacological Tools and Drugs

Carmine – overlooked allergen in diagnostic of immediate and delayed idiopathic hypersensitivity

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