Allergic contact dermatitis from doxepin

Long‐lasting allergic contact dermatitis and positive patch test reactions to doxepin

“…but 0.5% pet. was also found suitable 7,8 . To our knowledge, the present report is the first to show strong (++) or extreme (+++) positive patch test reactions to a dilution series of doxepin down to 0.01% in pet.…”

Allergic contact dermatitis due to doxepin cream in a patient with dystrophic epidermolysis bullosa

“…Since becoming available in the UK in July 1998, there has been 1 published report of contact allergy to doxepin, also in a patient with dystrophic epidermolysis bullosa (1). Prior US experience suggests that many more such cases are likely (2).…”

Systemic allergic dermatitis from doxepin: A case report

“…A few case reports of ACD from topical doxepin have been published since its approval for short‐term (up to 8 days) management of pruritus in eczema 3–9 . The largest series concerned 26 cases, all of which involved long‐term use (>2 weeks) of doxepin 5% cream 3 .…”