Allergic contact dermatitis to epoxy resin in infusion sets of an insulin pump

Allergic contact dermatitis caused by isobornyl acrylate in OmniPod, an innovative tubeless insulin pump

“…48145–04–6) and its oligomers . Epoxy resin has also been reported as a culprit sensitizer . One case report described a patient who reacted to several (meth)acrylates, but the authors could not obtain samples of the glue components to complete the work‐up, as is unfortunately often the case…”

“…3,4 Epoxy resin has also been reported as a culprit sensitizer. 5 One case report described a patient who reacted to several (meth)acrylates, but the authors could not obtain samples of the glue components to complete the work-up, as is unfortunately often the case. 6 In 1995, contact allergy to IBOA was reported in 2 young women who developed eczema and abscesses around the injection sites of their insulin pumps.…”

Airborne contact dermatitis caused by microscopy immersion fluid containing epoxy resin

“…The importance of patch testing with the epoxy resin to which the patient has been exposed, in addition to the standard test, has been stressed (4). Epoxy resins are mainly found in 2-component adhesives, but many other sources have been identified, including medical and laboratory equipment (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17).…”

Epoxy Resins

“…Non-occupationally induced contact sensitivity has been reported from epoxy resin in medical devices, such as hemodialysis needles, polyvinyl ostomy bags, infusion sets of an insulin pump, nasal cannulae, pacemaker, and amputation prosthesis (Brandao and Pinto 1980;Romaguera and Grimalt 1981;Mann et al 1983;Beck et al 1985;Boom and van Driel 1985;O'Brien 1986;Requena et al 1986;Geldof et al 1989;Toome 1989;Ancona et al 1990;Ng et al 1998). Furthermore, numerous case reports present epoxy sensitisation due to hidden sources of epoxy resin, such as a one-pack epoxy glue (Dahlquist et al 1979a), oil painting (Conde-Salazar et al 1982), lamination of glass products (HeskeI1988), adhesive pIaster (DoomsGoossens et al 1993), bowls polish (Lyon et al 1998), a billiard cue (Gon~alo et al 1992), and microscopy immersion oils (Sommer et al 1997;Le Coz et al 1998).…”