Allergic Diseases in the Developing World: An Emerging Problem or an Overseen Issue?

Eghtesad, Sareh

doi:10.1007/978-3-030-31222-0_2

“…However, further studies with a greater sample size are required to assess the precise rate of allergies as presenting signs of IEI. The prevalence of allergic diseases has been previously assumed to be lower in the developing countries including Iran; nonetheless, recent reports have demonstrated an increasing trend, mainly due to environmental factors including urbanization and shifting toward the modern lifestyle and also increased awareness and registry of such complications [16].…”

Section: Discussionmentioning

confidence: 99%

The Prevalence of Atopic Manifestations in 313 Iranian Patients with Inborn Errors of Immunity

Ghaini¹,

Jamee²,

Mahdaviani³

et al. 2021

Int Arch Allergy Immunol

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Introduction: Inborn errors of immunity (IEIs) are rare inherited disorders with a broad spectrum of manifestations. Here, we aimed to delineate the atopy burden in a cohort of patients with IEIs. Methods: 313 patients with IEIs were enrolled in the study within a 9-years period, and data were collected via a questionnaire. All statistical analyses were performed using SPSS software (v. 25.0, Chicago, IL, USA). The statistical significance level was set at p < 0.05. Results: Overall, 51 out of 313 (16.3%) patients were identified to have atopic manifestations. Food allergy was detected in 34 (10.2%), atopic dermatitis in 21 (6.7%), as well as allergic asthma and allergic rhinitis each in 4 (1.3%) patients. The allergic disorders were reported as initial manifestations among 14 out of 35 (40.0%) atopic patients. Most of these 51 patients fell within the category of combined immunodeficiency (CID) (n = 38, 74.5%), followed by, severe CID (SCID) (n = 5, 9.8%), common variable immunodeficiency (n = 3, 5.9%), chronic granulomatous disease (n = 3, 5.9%), selective IgA deficiency (n = 1, 2.0%), and leukocyte adhesion defect (n = 1, 2.0%). No patient with Mendelian susceptibility to mycobacteria was found to have atopic manifestation. Atopic dermatitis (p = 0.001) and food allergy (p < 0.001) were both significantly higher in patients with CID than in other IEI groups. Among atopic patients with CID and SCID, food allergy and atopic dermatitis were the most prevalent comorbidities. Discussion/Conclusion: Atopic diseases may contribute to the clinical picture of IEIs, particularly in patients with CID. Atopy in association with other warning signs of IEIs increases the possibility of an underlying IEI.

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Epidemiological profile of allergic respiratory disease in Mexican children

Gonzalez-Diaz,

Macias- Weinmann,

De Lira-Quezada

et al. 2024

Rev Alerg Mex

0

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Objective: Report the prevalence and severity of the most common allergic diseases in children living in Monterrey, México. Methods: Cross-sectional multi-center survey on the most common allergic diseases, completed by parents of 6-7-year-old children and by 13-14- year-old adolescents in the Monterrey metropolitan area, between January 2018 and December 2019. Results: A total of 3,044 questionnaires were eligible for the analysis. Among children between 6-7 years old, 30.2% (n = 143/473) presented wheezing at any time in their life; with a higher prevalence in the male population. In the adolescent group, 26.4% reported having experienced wheezing at some point in their life, with a slight predominance in the female group (54.9%). Conclusions: Knowing the prevalence of allergic diseases in our population gives us tools to generate strategies that allow us to provide the best quality healthcare to our patients. Keywords: Asthma; Rhinitis; Eczema; Wheezing; Allergy And Immunology; Child.

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Epidemiological profile of allergic respiratory disease in Mexican children

Gonzalez-Diaz,

Macias- Weinmann,

De Lira-Quezada

et al. 2024

Rev Alerg Mex

0

View full text Add to dashboard Cite

Objective: Report the prevalence and severity of the most common allergic diseases in children living in Monterrey, México. Methods: Cross-sectional multi-center survey on the most common allergic diseases, completed by parents of 6-7-year-old children and by 13-14- year-old adolescents in the Monterrey metropolitan area, between January 2018 and December 2019. Results: A total of 3,044 questionnaires were eligible for the analysis. Among children between 6-7 years old, 30.2% (n = 143/473) presented wheezing at any time in their life; with a higher prevalence in the male population. In the adolescent group, 26.4% reported having experienced wheezing at some point in their life, with a slight predominance in the female group (54.9%). Conclusions: Knowing the prevalence of allergic diseases in our population gives us tools to generate strategies that allow us to provide the best quality healthcare to our patients. Keywords: Asthma; Rhinitis; Eczema; Wheezing; Allergy And Immunology; Child.

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Allergic Diseases in the Developing World: An Emerging Problem or an Overseen Issue?

Cited by 4 publications

References 289 publications

The Prevalence of Atopic Manifestations in 313 Iranian Patients with Inborn Errors of Immunity

The Prevalence of Atopic Manifestations in 313 Iranian Patients with Inborn Errors of Immunity

Epidemiological profile of allergic respiratory disease in Mexican children

Epidemiological profile of allergic respiratory disease in Mexican children

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