Allergic sinusitis: Clinical and immunopathologic characteristics

Feohifomicosis nasal por Curvularia spicifera en un paciente pediátrico con neutropenia y leucemia mieloide aguda

“…En un caso se reportó una recurrencia a pesar de la terapia y posterior mejoría sintomática, pero sin resolución completa y con cultivos persistentemente positivos 22 . Los tres pacientes que no recibieron antifúngicos presentaron sinusitis que se manejaron de forma quirúrgica con buena respuesta 10,11 . Sin embargo, uno de ellos tuvo una recurrencia que requirió cirugía y antifúngicos 11 .…”

Recurrent Allergic Fungal Sinusitis Sequentially Caused byExserohilumandBipolaris

“…Allergic fungal sinusitis is one of four types of fungal disease of the paranasal sinuses. 1,13,18 It is associated with allergies or asthma and is characterized by chronic colonization of the lumen with massive mucus and eosinophilic leukocyte exudation with no tissue invasion. Not all allergic fungal sinusitis are associated with Aspergillus species, and the isolation of the etiologic agent in culture is necessary to distinguish the various fungal agents.…”

“…Nonallergic individuals would expel the inhaled fungus without consequence. 1,18 Noninvasive allergic fungal sinusitis is an example of a disease due solely to a hypersensitive response to the colonization of an inhaled fungus. Concurrent mixed infections at the same time and from different sites in the same patient caused by more than one genus of dematiaceous fungus have been reported in both healthy 6 and immunocompromised patients.…”

“…10 During the past several years, there has been an increase in the frequency of cases of phaeohyphomycosis caused by the members of the genera Bipolaris and Exserohilum. 11 Allergic phaeohyphomycosis caused by dematiaceous fungi, such as Alternaria, Bipolaris, Cladosporium, Curvularia, and Exserohilum species, are capable of localized colonization, and infection of the paranasal sinuses in both immunocompetent [3][4][5][6][7][8][9][11][12][13][14][15][16][17][18][19][20][21] and immunocompromised hosts. [21][22][23][24] Intracranial extension of the dematiaceous fungi in patients with allergic fungal sinusitis has been reported in the literature, 4,13,19,20 which illustrates how dangerous these fungi can become.…”

Claviceps purpurea e Bipolaris sp. como causa de ergotismo em bovinos no estado de Santa Catarina

“…Algumas espécies de Bipolaris são descritas como causadores de enfermidades em animais (Waurzyniak et al 1992, Quinn et al 2005a) e humanos (Gourley et al 1990, Saubolle & Sutton 1996, Koshy & Daniel 2002. Bipolaris spicifera é descrito como agente causador de micose subcutânea em gatos, cães, equinos, bovinos (Quinn et al 2005b) além de ocasionar micetoma (Fontes & Abreu 2015), ceratomicose (Saha & Das 2005), feohifomicose nasal em humanos (Rao et al 1989) e lesões de pele e encéfalo secundárias a embolia fúngica em humanos imunossuprimidos (Teran et al 2014).…”