Allergy to dogfish

Immunological cross-reactivity between four distant parvalbumins—Impact on allergen detection and diagnostics

“…However reports on allergenic parvalbumin from cartilaginous fish are limited (Cai et al, 2010;Rodríguez et al, 2003) and attempts to detect parvalbumin from cartilaginous fish with cross-reacting antibodies have not been very successful (Saptarshi et al, 2014). As expected all five cartilaginous fish species where not detect by immunoblotting, however, all were detected to a certain degree by the indirect ELISA method employed, demonstrating that antibody binding to parvalbumin seem to be lost under denaturing conditions.…”