Alopecia in a Boy With Nephrotic Syndrome

Black dots on the scalp of a child

“…Topical antifungal drugs are unable to sufficiently penetrate the hair shaft to clear the infection and used alone are not suitable 1. Treatment requires a combination of oral and topical antifungal drugs 14…”

Lung Volume Reduction Coils for Severe Emphysema

“…To prevent cyclosporine toxicity, decreasing the dose of concomitant itraconazole is not recommended, as its efficacy strongly correlates with plasma concentrations. 1 Alternatively, decreasing the dose of cyclosporine by 50% to 60% on initiation of itraconazole has been recommended. 2 But there is considerable interpatient…”