Alteramine ? A new alkaloid fromThermopsis alterniflora

Shaimardanov, R. A.; Iskandarov, S.; Yunusov, S. Yu.

doi:10.1007/bf00941712

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…The number of cytisine derivatives substituted on ring C (except on the nitrogen atom) is rather restricted. Some of them are natural products: 4-allylcytisine 225 was extracted from Sophora Secundiflora, Bolusanthus Speciosus, and Argyrolobium uniflorum, and N -methyl-4-allylcytisine (“tinctorine”) 226 was from Thermopsis Alterniflora, Argyrolobium uniflorum, and Clathropis glaucophylla . 4-Methyl and 4-allylcytisines 224 and 225 have been prepared in three steps from (−)-cytisine according to a method previously described .…”

Section: (−)-Cytisine Derivatives: Synthesis and Propertiesmentioning

confidence: 99%

(−)-Cytisine and Derivatives: Synthesis, Reactivity, and Applications

et al. 2013

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Section: (−)-Cytisine Derivatives: Synthesis and Propertiesmentioning

confidence: 99%

(−)-Cytisine and Derivatives: Synthesis, Reactivity, and Applications

et al. 2013

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“…Chemical investigations revealed the presence of alkaloids (cytisine, methyl cytisine, thermopsine, alteramine, dimethamine, pachycarpine), flavonoids (crotonoyl thermopsoside, crotonoylcosmosiin, formononetin, chrysoeriol, apigenin, luteolin, thermopsoside and cynaroside. ), organic acids, sugars and resin in epigeal parts [2][3][4][5][6][7]. Cytisine is one of its important alkaloids used for acute respiratory problems and withdrawal of smoking cessation [1,8,9].…”

Section: Introductionmentioning

confidence: 99%

Quantitative Analysis of Cytisine in Thermopsis Alterniflorae Using High-Performance Thin-Layer Chromatography

GADHVI

Modi

Mamta

2023

Int J Curr Pharm Sci

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Objective: An optimized high-performance thin-layer chromatography (HPTLC) method has been established for the quantification of cytisine in Thermopsis alterniflorae Regel and Schmalh. Methods: Alcoholic extract of the aerial parts were prepared using Soxhlet extraction method. Separation was achieved on silica gel 60 F254 HPTLC plates using toluene-ethyl acetate-diethyl amine (7:2:1, v/v) as the mobile phase. The quantitation of cytisine was carried out using densitometric scanning at 545 nm after derivatization using Dragendorff’s reagent. Results: The linear regression analysis data for the calibration plot showed a good linear relationship (r2 = 0.9849) in the concentration range 10 to 15 µg/spot. The method was validated for precision, repeatability, accuracy, specificity, limit of detection and limit of quantification. The average recovery was 99.0899% indicating good accuracy. The percentage yield of cytisine obtained was 0.5075+0.0135 % w/w. Conclusion: The proposed HPTLC method was found to be simple, sensitive, accurate, reproducible, and robust.

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Alteramine ? A new alkaloid fromThermopsis alterniflora

Cited by 2 publications

References 2 publications

(−)-Cytisine and Derivatives: Synthesis, Reactivity, and Applications

(−)-Cytisine and Derivatives: Synthesis, Reactivity, and Applications

Quantitative Analysis of Cytisine in Thermopsis Alterniflorae Using High-Performance Thin-Layer Chromatography

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