Alteration in autonomic reactivity from hypothyroid to euthyroid status

Linear and nonlinear analyses of heart rate variability following orthostatism in subclinical hypothyroidism

“…Only 5 (8%) were newly diagnosed untreated patients and were oriented to search for an endocrinologist. Therefore, as it has been reported that the replacement treatment with levothyroxine may cause an improvement in autonomic abnormalities following euthyroidism restoration, [42,50–52] it is not possible to conclude whether the results represent the medication effect or the hypothyroid state dysfunction itself.…”