Alteration in choroidal blood flow produced by local pressure

Abstract

Brief pressure on the RPE and choroid causes immediate reduction in flow through choroidal vessels, which appears to be due to local thrombosis in small segments of these vessels that resolves slowly. This may reflect a tendency for thrombi to form rapidly in choroidal vessels; it may also depend on neural reflexes causing vasoconstriction. The long time course of recovery could result in retinal ischemia and may underlie the pathophysiology of other pressure insults to the choroid.

Analysis of the Intraocular Jet Flows and Pressure Gradients Induced by Air and Fluid Infusion: Mechanism of Focal Chorioretinal Damage

“…Ivert et al 23 showed that choroidal blood flow could be affected by local pressure. A glass rod was used to exert brief pressure (below 1 mm Hg) on the RPE and choroid.…”