Alterations in early auditory evoked potentials and brainstem transmission time associated with tinnitus residual inhibition induced by auditory electrical stimulation

Mahmoudian, Saeid; Lenarz, Minoo; Esser, Karl‐Heinz; Salamat, Behrouz; Alaeddini, Farshid; Dengler, Reinhard; Farhadi, Mohammad; Lenarz, Thomas

doi:10.5935/0946-5448.20130009

Cited by 8 publications

(26 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among the studies that evaluated hearing, 17 studies used hearing status as a way to match controls to the tinnitus group. Three articles (Maurizi et al, 1985; Mahmoudian et al, 2013; Kim et al, 2016) did not have a control group and focused their comparisons on subgroups of tinnitus patients based on the configuration of the audiogram. These 17 studies either ensured that they used only a normal hearing population for both the tinnitus and control groups ( n = 12), or a mixture of normal hearing and hearing loss for the control and tinnitus groups, matched based on the degree of hearing loss ( n = 5).…”

Section: Resultsmentioning

confidence: 99%

“…Presentation levels were generally high (>80 dB) and were either expressed in HL ( n = 8), nHL ( n = 6), or SPL ( n = 7). Of the six studies reporting stimulus level in dB nHL, three reported using their own subjects to determine the minimum click intensity in dB SPL that elicited a behavioral response (Maurizi et al, 1985; Gu et al, 2012; Mahmoudian et al, 2013). When filter characteristics were reported ( n = 16), the cutoff frequency of the high-pass filters ranged from 5 to 200 Hz and from the 1,500 to 5,000 Hz for the low-pass filters.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What?

Milloy

Fournier

Benoît

et al. 2017

Front. Aging Neurosci.

View full text Add to dashboard Cite

The auditory brainstem response (ABR) in tinnitus subjects has been extensively investigated over the last decade with the hopes of finding possible abnormalities related to the pathology. Despite this effort, the use of the ABR for tinnitus diagnosis or as an outcome measure is under debate. The present study reviewed published literature on ABR and tinnitus. The authors searched PubMed, MedLine, Embase, PsycINFO, and CINAHL, and identified additional records through manually searching reference lists and gray literature. There were 4,566 articles identified through database searching and 151 additional studies through the manual search (4,717 total): 2,128 articles were removed as duplicates, and 2,567 records did not meet eligibility criteria. From the final 22 articles that were included, ABR results from 1,240 tinnitus subjects and 664 control subjects were compiled and summarized with a focus on three main areas: the participant characteristics, the methodology used, and the outcome measures of amplitude and/or latency of waves I, III, and V. The results indicate a high level of heterogeneity between the studies for all the assessed areas. Amplitude and latency differences between tinnitus and controls were not consistent between studies. Nevertheless, the longer latency and reduced amplitude of wave I for the tinnitus group with normal hearing compared to matched controls was the most consistent finding across studies. These results support the need for greater stratification of the tinnitus population and the importance of a standardized ABR method to make comparisons between studies possible.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Auditory Brainstem Responses in Tinnitus: A Review of Who, How, and What?

Milloy

Fournier

Benoît

et al. 2017

Front. Aging Neurosci.

View full text Add to dashboard Cite

show abstract

“…( 50 – 52 ) – nor hearing thresholds – comparable between groups in Ref. ( 48 , 50 , 52 ), not comparable between groups in Ref. ( 49 ); unknown in Ref.…”

Section: Gap Detection In Humans With Tinnitusmentioning

confidence: 97%

“…Mahmoudian et al ( 50 ) examined the cortical correlates of gap detection in tinnitus participants and matched controls using electroencephalography (EEG). More specifically, the mismatched negativity (MMN) waves between standard and deviant sounds were compared between tinnitus and controls without tinnitus.…”

Section: Gap Detection In Humans With Tinnitusmentioning

confidence: 99%

“…However, two other factors might be involved, namely, task requirements and background noise levels. Indeed, two studies ( 49 , 52 ) that used tasks requiring high-level cognitive resources found not gap detection deficits [an exception is the study of Mehdizade Gilani et al ( 51 )] whereas the two studies ( 48 , 50 ) that used tasks not requiring such resources, namely startle reflex and pre-attentional processing, found gap detection deficits although not specific to the tinnitus frequency. It is possible that the requirement – or lack thereof – of attentional resources on a simple task, that is, behavioral performance in detecting a gap, can overcome subtle gap deficits.…”

Section: Gap Detection In Humans With Tinnitusmentioning

confidence: 99%

See 1 more Smart Citation

Gap-Prepulse Inhibition of the Acoustic Startle Reflex (GPIAS) for Tinnitus Assessment: Current Status and Future Directions

Galazyuk

Hébert

2015

Front. Neurol.

View full text Add to dashboard Cite

The progress in the field of tinnitus largely depends on the development of a reliable tinnitus animal model. Recently, a new method based on the acoustic startle reflex modification was introduced for tinnitus screening in laboratory animals. This method was enthusiastically adopted and now widely used by many scientists in the field due to its seeming simplicity and a number of advantages over the other methods of tinnitus assessment. Furthermore, this method opened an opportunity for tinnitus assessment in humans as well. Unfortunately, multiple modifications of data collection and interpretation implemented in different labs make comparisons across studies very difficult. In addition, recent animal and human studies have challenged the original “filling-in” interpretation of the paradigm. Here, we review the current literature to emphasize on the commonalities and differences in data collection and interpretation across laboratories that are using this method for tinnitus assessment. We also propose future research directions that could be taken in order to establish whether or not this method is warranted as an indicator of the presence of tinnitus.

show abstract