Alterations in Hematological and Serum Biochemical Parameters of Sahel Goats with Clinical Mastitis

Abba, Yusuf

doi:10.9790/2380-0447477

Cited by 3 publications

(3 citation statements)

References 22 publications

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“…There was a significant decline in Haemoglobin, Total Erythrocyte Count, Packed Cell Volume, while elevated levels in Total Leucocyte count and Neutrophils with significant decrease in lymphocyte count and a non-significant reduction in eosinophils and monocyte value was observed in clinical mastitis affected goats as compared to healthy control (Table 4). These findings were in agreement with Abba et al (2013) [1] & Singh et al (2018) [22] who observed decreased Hb levels, leukocytosis, neutrophilia and lymphopenia in mastitis affected goats.…”

Section: Resultssupporting

confidence: 92%

Diagnostic studies on clinical mastitis in goats

Suman,

Lakshmi,

Nagaraj

et al. 2024

Int. J. Adv. Biochem. Res.

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During the investigation" Diagnostic studies on clinical mastitis in goats'' was under taken on 260 quarters of 130 goats which were screened for clinical mastitis (CM), using different diagnostic tests out of which 54 quarters of 33 goats were found positive for clinical mastitis based on bacterial culture examination. Clinical signs recorded were inappetence/anorexia, decreased milk production, swollen and painful udder, pyrexia, warmthness of udder, pale mucous membrane, udder erythema, dehydration, asymmetry of teats, depression and hardness of udder. Vital parameters like meanrectal temperature (ºF), pulse rates (perminute), respiratory rates (breath/min.) were non-significantly increased along with decreased rumen motility in mastitis affected goats as compared with healthy control. The conjunctival mucous membrane was pale. Physical examination of milk samples revealed milk colour changes, consistency along with appearance of flakes and clots. Qualitative changes of milk in CM affected goats were assessed based on MCMT, SCC and milk pH. Hematological studies of CM affected goats revealed significant reduction in mean levels of hemoglobin, TEC, PCV, eosinophils, monocytes with leukocytosis, neutrophilia and lymphopenia. The bacteria found from clinical mastitis affected quarter milk samples as single infection include coagulase negative Staphylococcus spp., Escherichia coli spp., Klebsiella spp., Streptococcus spp. and coagulase positive Staphylococcus spp. The bacteria identifies in mixed infection were coagulase negative Staphylococcus spp.in combination with Escherichia coli, Coagulase negative Staphylococcus spp. with Klebsiella spp., E. coli with Streptococcus spp., Coagulase negative Staphylococcus spp. with Streptococcus spp. and coagulase positive Staphylococcus spp., with Escherichia coli 7.41, 5.56, 3.70, 3.70 and 1.85 percent respectively.

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Section: Resultssupporting

confidence: 92%

Diagnostic studies on clinical mastitis in goats

Suman,

Lakshmi,

Nagaraj

et al. 2024

Int. J. Adv. Biochem. Res.

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“…Disease-related stress and neutrophilia (subsequent leukocytosis) as well as lymphopenia may develop as a result of the endogenous production of corticosteroids in the mastitic group ( Duncan, 1994 ; Kaneko, 1997 ). Our finding was similar to that obtained in mastitis in goats ( Abba, 2013 ), in cattle ( Saleh et al ., 2022 ), and in camels ( Darwish, 2023 ).…”

Section: Discussionsupporting

confidence: 93%

“…Anorexia and renal dysfunctions may be acceptable causes for these deficiencies. Similar opinions were mentioned in mastitis in Sahel goats ( Abba, 2013 ) and in she camels ( Darwish, 2023 ).…”

Section: Discussionsupporting

confidence: 69%

Individual genomic loci, transcript level and biochemical profile of immune and antioxidant markers associated with genetically identified bacterial mastitis in Shami goats in Egypt

Ebissy,

Darwish,

Hafez

et al. 2024

Open Vet J

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Background: Mastitis in goats is unquestionably a grave concern, with far-reaching implications for both animal well-being and productivity, while also presenting a potential threat to public health. Aim: The study aimed to compare between culture methods and multiplex PCR (m-PCR) in detection of the most 3 common mastitis causing pathogens (Staphylococcus aureus, E. coli, Streptococcus spp) and investigating the gene expression, single nucleotide polymorphisms (SNPs), serum concentrations of immunological and antioxidant indicators linked to mastitis in Shami goats. Methods: One hundred Shami does (fifty Shami goats with clinical mastitis and fifty normal goats taken as control group). The culture methods and m-PCR analysis were used to find the bacteria in the milk samples.Blood samples were obtained in order to assess some hemato-biochemical parameters, detect SNPs, and determine the expression of certain immunological and antioxidant indicators in the genes. Results: Culture method detected the pathogens causing mastitis in 90% of the milk samples, but m-PCR detected them in 100% of the milk samples. SNPs linked to mastitis resistance/susceptibility in examined does were detected through DNA sequencing of immunological and antioxidant indicators. Magnitude of gene expression varied significantly between the resistant and mastitis affected groups. Significant (P˂0.05) elevations were noticed in WBCs count, mainly neutrophils count, serum levels of BHB, NEFA, triglycerides, LDL-C, AST, ALT, ALP, creatinine, total protein, globulin, Ca, K, GPx, MDA, acute phase proteins and cytokines in mastitis affected does as compared to control. While RBCs count, PCV%, lymphocytes count, serum concentration of glucose, cholesterol, HDL-C, albumin, Na, Cl, P, GSH, SOD, catalase significantly (P˂0.05) diminished in mastitis affected does compared to healthy ones. APPs and pro-inflammatory cytokines scored high sensitivities and NPVs but TNF-α and SAA had the highest percentages of increase. Conclusion: The study confirmed that m-PCR is the most sensitive method for bacteria identification (S. aureus, E. coli and Strept. spp.) while SNPs in antioxidant and immunological genes may be important genetic indicators for mastitis risk or resistance in Shami does. In order to establish an effective management plan and forecast the most sensitive risk time for illness onset, gene expression profiles of the tested genes may also be employed as proxy biomarkers. TNF-α and SAA may be precious indicators for detection of caprine mastitis.

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Effects of supplementing probiotics and concentrate on intake, growth performance and blood profile of intensively kept Sahelian does fed a basal diet of Brachiaria decumbens grass

Osman

Osafo

Attoh-Kotoku

et al. 2023

Journal of Applied Animal Research

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Alterations in Hematological and Serum Biochemical Parameters of Sahel Goats with Clinical Mastitis

Abstract: Mastitis is a widespread disease of the dairy goats associated with alterations in the physical

Cited by 3 publications

References 22 publications

Diagnostic studies on clinical mastitis in goats

Diagnostic studies on clinical mastitis in goats

Individual genomic loci, transcript level and biochemical profile of immune and antioxidant markers associated with genetically identified bacterial mastitis in Shami goats in Egypt

Effects of supplementing probiotics and concentrate on intake, growth performance and blood profile of intensively kept Sahelian does fed a basal diet of Brachiaria decumbens grass

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