“…1). 3D kinematic analysis of individual bones is valid and reliable only via invasive approaches such as intracortical pins (Arndt et al, 2007;Lundgren et al, 2008;Westblad et al, 2002), actuator-controlled gait simulators in vitro (McKearney et al, 2019;Nester et al, 2007;Okita et al, 2013;Saito et al, 2019), quasi-dynamic radiostereometric analysis (RSA) which involves insertion of intracortical markers (Lundberg, 1989;Lundberg et al, 1989aLundberg et al, , 1989bLundberg et al, , 1989c and bi-planar video fluoroscopy (Komistek et al, 2000;Lenz et al, 2021). Intracortical pins, actuator controlled gait simulators and RSA methods all track bones very precisely by utilizing at least three non-collinear markers inserted surgically into each bone segment of interest.…”