Alternating bioactivity of multilayer thin films assembled from charged derivatives of chitosan

Channasanon, Somruethai; Graisuwan, Wilaiporn; Kiatkamjornwong, Suda; Hoven, Voravee P.

doi:10.1016/j.jcis.2007.07.071

Cited by 39 publications

(27 citation statements)

References 33 publications

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“…Chitosan is a promising implantable material that derives potential from its gel-forming properties and cationic nature that allows it to form insoluble ionic complexes with a variety of anionic polymers. Primary amino groups in the chitosan structure can be easily derivatized with useful biological ligands, or modified with other entities to alter mechanical and degradation properties, as well as protein adsorption properties [1][2][3]. In addition, the material has been shown to promote wound healing, and exhibits a minimal foreign body response with accelerated angiogenesis [4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Branched chitosans II: Effects of branching on degradation, protein adsorption and cell growth properties

Aggarwal

Matthew

2009

Acta Biomaterialia

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Section: Introductionmentioning

confidence: 99%

Branched chitosans II: Effects of branching on degradation, protein adsorption and cell growth properties

Aggarwal

Matthew

2009

Acta Biomaterialia

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“…Similar result reported by Channasanon et al . also indicated that the chitosan was bonded to the surface of PET that could significantly increase the adsorption of protein such as bovine serum albumin and fibrinogen 32. On the other hand, adsorption on PET‐NANA was lowered by 3.6 and 11.3% for HSA and HPF, respectively, compared to PET‐DAH.…”

Section: Resultsmentioning

confidence: 99%

Bioconjugatable Azo‐Based Dark‐Quencher Dyes: Synthesis and Application to Protease‐Activatable Far‐Red Fluorescent Probes

Chevalier

Massif

Renard

et al. 2012

Chemistry A European J

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We describe the efficient synthesis and one-step derivatization of novel, nonfluorescent azo dyes based on the Black Hole Quencher-3 (BHQ-3) scaffold. These dyes were equipped with various reactive and/or bioconjugatable groups (azido, α-iodoacetyl, ketone, terminal alkyne, vicinal diol). The azido derivative was found to be highly reactive in the context of copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions and allowed easy synthetic access to the first water-soluble (sulfonated derivative) and aldehyde-modified BHQ-3 dyes, the direct preparation of which failed by means of conventional azo-coupling reactions. The aldehyde- and α-iodoacetyl-containing fluorescence quenchers were readily conjugated to aminooxy- and cysteine-containing peptides by the formation of a stable oxime or thioether linkage, respectively. Further fluorescent labeling of the resultant peptide conjugates with red- or far-red-emitting rhodamine or cyanine dyes through sequential and/or one-pot bioconjugations, led to novel Förster resonance energy transfer (FRET) based probes suitable for the in vivo detection and imaging of urokinase plasminogen activator, a key protease in cancer invasion and metastasis.

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“…Charged derivatives of chitosan, N-sulfofurfuryl chitosan and N-[(2-hydroxyl-3-trimethylammonium)propyl]chitosan chloride, were prepared by Channasanon et al (2007). The bioactivity of these films on the treated PET substrate was tested against selected proteins having a distinctive size and charge.…”

Section: Action Against Plant Pathogensmentioning

confidence: 99%

Bioactivity of Chitosan Derivative

Prabaharan

2014

Polysaccharides

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Chitosan, a natural-based polymer obtained by alkaline deacetylation of chitin, is composed of glucosamine and N-acetylglucosamine monomers. Chitosan and its derivatives have a great potential for a wide range of applications in biomedical, pharmaceutical, food, cosmetics, and environmental fields due to its biodegradability, biocompatibility, nontoxicity, and versatile chemical and physical properties. For a breakthrough in utilization, especially in the biomedical field, chemical modification of chitosan will be a key point that can introduce desired properties and enlarge the field of the potential applications of chitosan. Different approaches have been reported to prepare chitosan derivatives and chitosan oligomers with low, medium, and high molecular weights. In this chapter, the properties such as biodegradation, antimicrobial activity, anti-inflammatory and tissue regeneration activity, wound-healing properties, antioxidant activity, and antitumor activity of chitosan and its derivatives are discussed in detail.

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Alternating bioactivity of multilayer thin films assembled from charged derivatives of chitosan

Cited by 39 publications

References 33 publications

Branched chitosans II: Effects of branching on degradation, protein adsorption and cell growth properties

Branched chitosans II: Effects of branching on degradation, protein adsorption and cell growth properties

Bioconjugatable Azo‐Based Dark‐Quencher Dyes: Synthesis and Application to Protease‐Activatable Far‐Red Fluorescent Probes

Bioactivity of Chitosan Derivative

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