Alzheimer's Association Update

Aggregates of hyperphosphorylated tau (PHF-tau), such as neurofibrillary tangles, are linked to the degree of cognitive impairment in Alzheimer's disease. We have recently reported early clinical results of a novel PHF-tau targeting PET imaging agent, [F18]-T807. Since then, we have investigated a second novel PHF-tau targeting PET imaging agent, [F18]-T808, with different pharmacokinetic characteristics, which may be favorable for imaging Alzheimer's disease and other tauopathies. Here, we describe the first human brain images with [F18]-T808.

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Early Clinical PET Imaging Results with the Novel PHF-Tau Radioligand [F18]-T808

Chien

Szardenings

Bahri

et al. 2013

JAD

443

193

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Alzheimer's Association Update

Cited by 1 publication

References 5 publications

Early Clinical PET Imaging Results with the Novel PHF-Tau Radioligand [F18]-T808

Early Clinical PET Imaging Results with the Novel PHF-Tau Radioligand [F18]-T808

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