Ambiguities in Ab Initio Phasing

In contrast to the immunosuppressive effects of C2-ceramide (C2-Cer), alpha-galactosylceramides with ceramides having more than 10 carbons in fatty acid chains have immunostimulatory activities. We therefore synthesized alpha- and beta-galactosylated C2-Cers in order to examine their effects on the immune system. beta-Galactosylated C2-Cer and C2-Cer suppressed the allogeneic mixed leukocyte reaction (MLR) responses, but alpha-galactosylated C2-Cer stimulated the MLR response.

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Effects of α- and β-Galactosylated C2-Ceramides on the Immune System

Sakai

Ueno

Natori

et al. 1998

J. Med. Chem.

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Ambiguities in Ab Initio Phasing

Cited by 1 publication

References 10 publications

Effects of α- and β-Galactosylated C2-Ceramides on the Immune System

Effects of α- and β-Galactosylated C2-Ceramides on the Immune System

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