Amebiasis Presenting as Acute Appendicitis

Andrade, Javier; Mederos, Raul; Rivero, Haidy G.; Sendzischew, Morgan; Soaita, Mauela; Robinson, Morton J.; Sendzischew, Harry; Danielpour, Payman J.

doi:10.1097/smj.0b013e318158326f

Cited by 10 publications

(5 citation statements)

References 8 publications

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“…Two of the early studies reported results from barium swallow radiography [39, 40], which was later replaced by imaging analysis. Among the seven patients with findings reported from ultrasonography and/or computed tomography scanning, acute appendicitis was diagnosed in four, periappendicular abscess in two, and a right abdomen lower quadrant mass in one [1, 2, 8, 9, 17, 18, 25]. The final diagnoses for the overall patients included acute appendicitis (167/172, 97.0 %), of whom 6 % had complicated acute appendicitis, including a periappendicular abscess, periappendicular mass, and perforated appendicitis (Table 2).…”

Section: Resultsmentioning

confidence: 99%

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Amebic Acute Appendicitis: Systematic Review of 174 Cases

2013

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Appendectomy specimens should be routinely sent for histopathologic examination. In the case of suspected amebic acute appendicitis, extra precautions-early appendectomy, metronidazole for antibiotic prophylaxis, wet-preparation examination, obtaining a timely pathology result, increasing the awareness of uncommon complications of appendectomy-can hasten appropriate therapeutic intervention and improve outcome.

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Section: Resultsmentioning

confidence: 99%

“…No restrictions were made on language, country, or journal. A total of 171 articles were retrieved for review, and 42 articles [1–42] were selected for inclusion in the analysis (Fig. 1).…”

Section: Methodsmentioning

confidence: 99%

Amebic Acute Appendicitis: Systematic Review of 174 Cases

2013

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“…Very rarely (<0.5% cases) [ 3 ], the disease takes a fulminant course leading to the development of fulminant necrotising amoebic colitis, which causes gangrenous necrosis of the involved large bowel. In most of the cases reported, only a segment of the large bowel was involved; the involvement of the whole of the large bowel, as in our case is very rare.…”

Section: Introductionmentioning

confidence: 99%

Fulminant Necrotising Amoebic Colitis of Whole of Large Bowel: A Rare Complication of a Common Infectious Disease

Beg

Bains

Mahajan

et al. 2020

Case Reports in Infectious Diseases

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Background. Fulminant necrotising amoebic colitis (FulNAC) is an uncommon and grave complication of a very common infectious disease widely prevalent in tropical countries. In most of the cases reported, only a segment of large bowel was gangrenous. The involvement of the whole of the large bowel, as in our case, is very rare and has very high mortality ranging from 55% to 100%. Case Summary. A 50-year-old gentleman presented with an acute abdomen with a history of crampy abdominal pain and passage of blood mixed with mucous and loose stools. After resuscitation and investigations, the patient was taken up for laparotomy and the findings showed that the caecum was sloughed off and the entire large bowel had multiple perforations. Subtotal colectomy with ileostomy was performed. Histopathological examination showed evidence of pancolitis with multiple colonies of amoebic trophozoites. Discussion. Entamoeba histolytica is a protozoon that affects the large intestine and liver in humans. There can be various presentations of amoebiasis: asymptomatic infection (90%), symptomatic noninvasive infection (6–8%), acute amoebic colitis (dysentery), or fulminant colitis with perforation. FulNAC is an uncommon complication, difficult to diagnose and treat, and associated with a high mortality rate, ranging from 55% to 100%. Conclusion. It is important to consider the possibility of fulminant necrotising amoebic colitis (FulNAC) as an uncommon and fatal complication of amoebiasis, especially in tropical countries, where amoebiasis is prevalent. Early diagnosis and antiamoebic treatment, along with urgent aggressive surgical resection of the involved segment and exteriorization of the proximal and distal bowel ends, are shown to reduce mortality.

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“…al., 2006;Livingston, et. al., 2007;Thalayasingam, 1985) and bacteria such as Campylobacter, Brucella and Salmonella (Campbell LK et al, 2006;Chan, et al, 1983;Lau, et al, 2005;Pourbagher, et al, 2006) as well as parasites (Andrade, et al, 2007;Elazary, et al,. 2005;Gali, et.…”

Section: Introductionmentioning

confidence: 99%

Unusual Histological Findings of the Appendix Following Appendectomy; A Ten Year Histopathologic Study

Igho¹

2012

CJBMSci

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IntroductionLesions of the appendix are common. The appendix is however exposed to other uncommon but deleterious lesions which if not detected early and prompt attention given immediately, may result in morbidity and mortality. Materials and methodsThis was a retrospective study which involved 1171 respondents aged between 2 and 80 years. Demographic data were obtained from the archives of the histopathology department of University of Benin Teaching Hospital. Results were analysed with chi square test and results presented in frequencies tables. ResultsA total of 1171 samples were analysed out of which 17 were miscellaneous findings. This included 7 diagnosed for chronic granulomatous. Parasitic infestations were observed in only two female and 1 male case respectively and their ages ranged between 21 and 50 years. One case each was seen in Carcinoid, intestinal necrosis, intestinal infarction, chronic HPV, haemorrhagic appendix (which was found in a patient between 70 and 80 year age range). ConclusionsThis study has further emphasised the need for routine histopathologic analysis of all appendices following appendectomies regardless of the macroscopic appearance.

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Amebiasis Presenting as Acute Appendicitis

Cited by 10 publications

References 8 publications

Amebic Acute Appendicitis: Systematic Review of 174 Cases

Amebic Acute Appendicitis: Systematic Review of 174 Cases

Fulminant Necrotising Amoebic Colitis of Whole of Large Bowel: A Rare Complication of a Common Infectious Disease

Unusual Histological Findings of the Appendix Following Appendectomy; A Ten Year Histopathologic Study

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