Aminolysis-Based Zwitterionic Immobilization on Polyethersulfone Membranes for Enhanced Hemocompatibility: Experimental, Computational, and Ex Vivo Investigations
Arash Mollahosseini,
Jumanah Bahig,
Ahmed Shoker
et al.
Abstract:Dialysis membranes are not hemocompatible with human blood, as the patients are suffering from the blood–membrane interactions’ side effects. Zwitterionic structures have shown improved hemocompatibility; however, their complicated synthesis hinders their commercialization. The goal of the study is to achieve fast functionalization for carboxybetaine and sulfobetaine zwitterionic immobilization on PES membranes while comparing the stability and the targeted hemocompatibility. The chemical modification approach… Show more
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