Amiodarone-lnduced Epididymitis

Hamoud, Kassem A.; Kaneti, Jacob; Smailowitz, Z; Lissmer, L.

doi:10.1159/000473805

Cited by 8 publications

(2 citation statements)

References 7 publications

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“…Also non-infectious causes such as post-traumatic epididymitis and obstructive pathology, Behcet’s disease and drug induced epididymitis may be encountered in differential diagnosis. The incidence of amiodarone epididymitis varies between 3% to 11% depending on the dosage and duration of usage ( 1 ) However, encountered only about 20-25 case reports in the evaluation of the literature ( 1 , 4 - 6 ). Chronic epididymyalgia in the absence of fever and leucocytosis is the chief symptom of this clinical entity.…”

Section: Discussionmentioning

confidence: 99%

Amiodarone Induced Epididymitis: A Case Report

Cicek¹,

Demir²,

Çoban³

et al. 2014

Iran Red Cres Med J

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Introduction:Amiodarone is an effective drug for life-threatening arrhythmias like recurrent ventricular fibrillation and atrial fibrillation. Amiodarone creates rarely genitourinary side effects are seen. These are epididymitis, testicular dysfunction and impotance. Amiodarone aggregates and triggers inflammation in the head of the epididym.Case report:We present the case of a patient who developed epididymitis after 17 months of amiodarone therapy, using a low dose (100 mg per day). Although cessation of medication or dose lowering was not performed, remission of the patient only by analgesics is a distinct case reported in urological literature.Conclusions:This case stresses the importance of considering an adverse effect of amiodarone treatment as a cause when making a differential diagnosis of epididymitis.

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Section: Discussionmentioning

confidence: 99%

Amiodarone Induced Epididymitis: A Case Report

Cicek¹,

Demir²,

Çoban³

et al. 2014

Iran Red Cres Med J

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“…Epididymitis can be a complication of medical treatments. Drug-induced epididymitis has been reported with the use of amiodarone (Gasparich et al, 1984;Hutcheson et al, 1998), a potent class III antidysrythmic benzofurane derivative for treating refractory ventricular and supraventricular cardiac arrhythmia (Hamoud et al, 1996;Gabal-Shehad and Monga, 1999). Postmortem examination of patients affected by amiodarone-induced epididymitis showed focal areas of epididymal fibrosis with lymphatic infiltration.…”

Section: Iatrogenic Epididymitismentioning

confidence: 99%

Epididymitis and Other Inflammatory Conditions of the Male Excurrent Ductal System

Chan

2002

The Epididymis: From Molecules to Clinical Practice

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Physiologically, the endocrinologic interplay between testes and pituitary gland results in the production of spermatozoa. Before serving their role in fertilizing oocytes, spermatozoa must exit the testis and pass through a complex excurrent ductal system that includes the efferent ductules, epididymis, and vas deferens, which leads to the ejaculatory duct. Pathological conditions in any part of the excurrent ductal system obviously may have a significant effect on spermatozoa transport, resulting in subfertility or infertility. In addition to spermatozoa, semen is composed of secretions from a series of glandular organs, including the prostate, seminal vesicles, the bulbourethral (Cowper) gland and periurethral (Littré) gland. Collectively, these organs are known as the male accessory glands.Various inflammatory conditions, including microbial infection, are by far the most common pathology encountered in the male reproductive system. The term male accessory gland inflammation 1 describes a broad spectrum of inflammatory conditions involving the male accessory glands. The prostate gland and the seminal vesicles together produce about 90% of the ejaculate volume. Although inflammatory conditions of these organs (prostatitis and seminal vesiculitis) are important clinical topics in andrology (Weidner et al, 1998a,b), in this review our discussion will focus mainly on the various inflammatory conditions of the excurrent ductal system. In Part I of this review, our discussion will focus mainly on the various inflammatory conditions of the epididymis and efferent ductile. In Part II, we will discuss the rarely described subject of vasitis and address the management issues and fertility effects of excurrent ductal inflammation.

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Inflammatory Conditions of the Male Excurrent Ductal System. Part I.

MD,

SCHLEGEL

2002

Journal of Andrology

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Amiodarone-lnduced Epididymitis

Cited by 8 publications

References 7 publications

Amiodarone Induced Epididymitis: A Case Report

Amiodarone Induced Epididymitis: A Case Report

Epididymitis and Other Inflammatory Conditions of the Male Excurrent Ductal System

Inflammatory Conditions of the Male Excurrent Ductal System. Part I.

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