Amplified neurobehavioral and hormonal alterations following the combination of prenatal and postnatal stress in first-time rats

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“…In the present study, we developed new dipharmacophore compounds based on substances with proven therapeutic activity, namely, the non-steroidal anti-inflammatory compound (NSAIDs), dexibuprofen, and the racetam compounds -nebracetam, which exhibits nootropic and cytoprotective effects, and also studied their anti-inflammatory effects on acute and chronic models of inflammation [22,23]. We accordingly studied the anti-inflammatory activity of a new dipharmacophore derivative dexibuprofen and nebracetam in modeling acute and chronic inflammation in the experiment on laboratory animals.…”