Amyloid Arthropathy (Shoulder Pad Sign) in a patient on dialysis due to Multiple Myeloma

Abstract

BACKGROUNDAmyloidosis is a heterogeneous group of diseases characterized by the extracellular deposition of low molecular weight proteins in tissues. Specially the AL type (mostly associated with multiple myeloma) and beta-2-microglobulin amyloidosis (as a consequence of dialysis) can affect the osteoarticular system. The "shoulder pad" sign is a rare pathognomonic finding for musculoskeletal involvement of the disease and could happen in both types of amyloidosis.