Amyotrophic lateral sclerosis

PAD2 dysregulation and aberrant protein citrullination feature prominently in reactive astrogliosis and myelin protein aggregation in sporadic ALS

“…To date, the disease has no cure. Treatments capable of halting or reversing the disease progression remain to be developed ( Akcimen et al, 2023 ; Mead et al, 2023 ; Younger and Brown Jr., 2023 ). Hence, continuous effort is required to push the frontiers of our understanding of the disease.…”