An Account on the Versatility of Dopamine as a Functional Monomer in Molecular Imprinting

Zaidi, Shabi Abbas

doi:10.1002/slct.201901029

Cited by 14 publications

(2 citation statements)

References 71 publications

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“…The self‐polymerization of dopamine (DA) on multiple substrates has become a simple and versatile method for synthesizing protein SMIPs. [ 128 ] However, due to its versatility, the prepared SMIPs have relatively high nonspecific binding, which has been an unfathomed problem. [ 129 ] Han et al.…”

Section: Synthesis Methods Of Protein Smipsmentioning

confidence: 99%

Nanomaterials‐Based Surface Protein Imprinted Polymers: Synthesis and Medical Applications

Pan

Hong

Xie

et al. 2020

Macro Chemistry & Physics

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Proteins are an essential part of organisms and play a very important role in life activities. Molecular imprinting technology (MIT) can prepare functional materials with specific identification abilities. In recent years, various molecularly imprinted materials have been widely used in the fields of solid‐phase extraction, bionic sensing, and on‐line analysis. Due to the limit of the properties of protein macromolecules, the development of MIT for protein molecules is relatively slow. With the continuous deepening on the research of nanomaterials and surface molecular imprinting technology, a large numbers of interesting and successful strategies appear on imprinted protein. Some surface protein imprinting materials with excellent properties and unique functions are applied in proteomics, biological imaging, medical diagnosis, and other fields, showing great potential application value. This paper summarizes the latest preparation and analysis strategies of surface protein imprinting based on nanomaterials, introduces medical application of protein imprinting materials in sample separation and purification, proteomics, biomedical and other aspects in recent years, and looks forward to the development opportunities and challenges in protein imprinting field.

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Section: Synthesis Methods Of Protein Smipsmentioning

confidence: 99%

Nanomaterials‐Based Surface Protein Imprinted Polymers: Synthesis and Medical Applications

Pan

Hong

Xie

et al. 2020

Macro Chemistry & Physics

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“…Removal of the template leaves behind a target specific cavity available for rebinding. (3) Finally, MIPs are exposed to a target containing sample where the cavity selectively uptakes the complementary target molecules [ 7 , 8 , 9 , 10 , 11 , 12 , 13 ]. A schematic representation of general MIP preparation is shown in Figure 1 .…”

Section: Introductionmentioning

confidence: 99%

Picomolar or beyond Limit of Detection Using Molecularly Imprinted Polymer-Based Electrochemical Sensors: A Review

et al. 2022

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Over the last decades, molecularly imprinted polymers (MIPs) have emerged as selective synthetic receptors that have a selective binding site for specific analytes/target molecules. MIPs are synthetic analogues to the natural biological antigen–antibody system. Owing to the advantages they exhibit, such as high stability, simple synthetic procedure, and cost-effectiveness, MIPs have been widely used as receptors/sensors for the detection and monitoring of a variety of analytes. Moreover, integrating electrochemical sensors with MIPs offers a promising approach and demonstrates greater potential over traditional MIPs. In this review, we have compiled the methods and techniques for the production of MIP-based electrochemical sensors along with the applications of reported MIP sensors for a variety of analytes. A comprehensive in-depth analysis of recent trends reported on picomolar (pM/10−12 M)) and beyond picomolar concentration LOD (≥pM) achieved using MIPs sensors is reported. Finally, we discuss the challenges faced and put forward future perspectives along with our conclusion.

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Advances in the selection of functional monomers for molecularly imprinted polymers: A review

Niu,

Du,

et al. 2024

J of Separation Science

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Molecularly imprinted polymers, a type of special polymer materials, are widely used in biosensing and other fields due to their ability to specifically recognize target molecules, often called “artificial receptors.”. Nowadays, researchers are constantly exploring new design and synthesis methods for molecularly imprinted materials to improve the selectivity and sensitivity of molecularly imprinted materials. Among them, the selection of functional monomers has attracted great attention. This review comprehensively analyzes and discusses the selection methods of functional monomers. The most commonly used functional monomers among different types of templates are screened based on the structural properties of the template molecules, including the selection of functional monomers among ion‐imprinted polymers, protein‐imprinted polymers, and bacterial imprinted polymers. The rich binding sites and functional group types of multifunctional monomers are also highlighted to advance the development of molecular imprinting technology. The article further explores the current challenges and prospects in the selection of functional monomers and emphasizes multiplex experiments and computer simulations as important directions for future research. This review provides comprehensive information and constructive guidelines for researchers in selecting functional monomers in areas such as analytical chemistry and biosensors.

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An Account on the Versatility of Dopamine as a Functional Monomer in Molecular Imprinting

Cited by 14 publications

References 71 publications

Nanomaterials‐Based Surface Protein Imprinted Polymers: Synthesis and Medical Applications

Nanomaterials‐Based Surface Protein Imprinted Polymers: Synthesis and Medical Applications

Picomolar or beyond Limit of Detection Using Molecularly Imprinted Polymer-Based Electrochemical Sensors: A Review

Advances in the selection of functional monomers for molecularly imprinted polymers: A review

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