An alternative therapy for post-traumatic endophthalmitis: Preserving capsule and primary intraocular lens implantation combined complete vitrectomy

Abstract

The purpose of the present study was to investigate whether preserving capsule and primary intraocular lens implantation in vitrectomy could influence the therapeutic effect and safety in the treatment of post-traumatic endophthalmitis. A prospective, randomized, controlled trial was performed in this study. A total of 89 patients with post-traumatic endophthalmitis that occurred between January 2008 and December 2010 were randomly divided into two groups: 45 patients underwent complete vitrectomy with preserved capsule and primary intraocular lens implantation, and 44 patients underwent complete vitrectomy with lensectomy and without intraocular lens implantation. There were no significant differences in patients' age, sex, injuries in detail, intraocular tamponade, culture-proven bacteria, and preoperative and postoperative visual acuity between two groups. No recurrence of bacterial infection was found in any case in both groups, and there was no severe complications happened in two groups during follow-up. Our results suggested that preserving capsule and primary intraocular lens implantation with complete vitrectomy in post-traumatic endophthalmitis was a safe and feasible surgery procedure with benefits in postoperative visual quality, which could be recommended as an alternative therapy.