An Antibacterial Bionic Periosteum with Angiogenesis-Neurogenesis Coupling Effect for Bone Regeneration
Peiqian Zhou,
Tuozhou Liu,
Wenbin Liu
et al.
Abstract:The periosteum, rich in neurovascular networks, bone
progenitor
cells, and stem cells, is vital for bone repair. Current artificial
periosteal materials face challenges in mechanical strength, bacterial
infection, and promoting osteogenic differentiation and angiogenesis.
To address these issues, we adjusted the electrospinning ratio of
poly-ε-caprolactone and chitosan and incorporated Zn doping
whitlockite with polydopamine coating into a nanofiber membrane. After
a series of characterizations, optimal result… Show more
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