An artificial anal sphincter based on a novel clamping mechanism: Design, analysis, and testing

Ding, Han; Yan, Guozheng; Wang, Zhiwu; Jiang, Pingping; Liu, Dasheng; Zhao, Kai; Ma, Jin

doi:10.1111/aor.13924

Cited by 7 publications

(4 citation statements)

References 25 publications

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“…Then, the clamping unit could perform the actions of clamping and relaxing as expected. Only in vitro preliminary tests have been conducted so far with promising results for maintaining continence and in terms of safe pressure 89 …”

Section: Novel Devicesmentioning

confidence: 99%

Artificial sphincters: An overview from existing devices to novel technologies

et al. 2022

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Artificial sphincters (ASs) are used to replace the function of the biological sphincters in case of severe urinary and fecal incontinence (UI and FI), and gastroesophageal reflux disease (GERD). The design of ASs is established on different mechanisms, e.g., magnetic forces or hydraulic pressure, with the final goal to achieve a implantable and durable AS. In clinical practice, the implantation of in‐commerce AS is considered a reasonable solution, despite the sub‐optimal clinical outcomes. The failure of these surgeries is due to the malfunction of the devices (between 46 and 51%) or the side effects on the biological tissues (more than 38%), such as infection and atrophy. Concentrating on this latter characteristic, particular attention has been given to the interaction between the biological tissues and AS, pointing out the closing mechanism around the duct and the effect on the tissues. To analyze this aspect, an overview of existing commercial/ready‐on‐market ASs for GERD, UI, and FI, together with the clinical outcomes available from the in‐commerce AS, is given. Moreover, this invited review discusses ongoing developments and future research pathways for creating novel ASs. The application of engineering principles and design concepts to medicine enhances the quality of healthcare and improves patient outcomes. In this context, computational methods represent an innovative solution in the design of ASs, proving data on the occlusive force and pressure necessary to guarantee occlusion and avoid tissue damage, considering the coupling between different device sizes and individual variability.

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Section: Novel Devicesmentioning

confidence: 99%

Artificial sphincters: An overview from existing devices to novel technologies

et al. 2022

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“…The corresponding relationship between the height of the intestinal content and the pressure vector was determined by in vitro experiments (details in Section 4 Figure 7). 20 And the distance thresholds D 0 and D 1 are obtained from calculation between P 0 , P 1 and the zero vector. Then the distance D is calculated between the vector to be determined and the zero vector.…”

Section: Methodsmentioning

confidence: 99%

Design and evaluation of perception reconstruction with sensor system for artificial anal sphincter based on vector similarity

et al. 2022

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Background Artificial organs are playing an increasingly important role in medical field. Artificial anal sphincter, as an example, is a widely used medical device for fecal incontinence. Though it could help patients maintain continence, the issue of perception reconstruction is still unsolved, which means that patients cannot control defecation as desired. Methods In this paper, a novel sensor system based on vector similarity has been analyzed and evaluated. The sensor system is a self‐packaged strain gauge sensor with a small size 14.5 mm × 6 mm, especially for medical device implanted in body to reconstruct perception function. In order to overcome the disadvantages of single threshold judgment, a more accurate and reliable judgment standard for content pressure detection in rectum is developed by using vector similarity method. Therefore, in the novel sensor system, standard multi‐parameters are comprehensive considered. Furthermore, weight‐optimization of sensors are investigated since each sensor has played a different role in detection. Finally, sensor calibration, in vitro and in vivo experiments are established. Results In sensor calibration, the result R2 > 0.99 presents the strain gauge pressure sensor has a good linearity. After that, a series of in vitro experiments have been conducted. The optimized sensor system shows a high accuracy rate in perception reconstruction, which is 87.5% on early warning and 95% on the alarm. In the following in vivo experiments. The results indicate that the average accuracy of the proposed perception reconstruction module has increased by 17.7%, compared with that without optimized sensor system. Conclusions All of these have proven that the novel perception reconstruction module with sensor system based on vector similarity is more acceptable and reliable.

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“…An experimental treatment has been proposed by Han et al with the use of prototype clamping devices that reform the anorectal angle. This helps improve continence even in the absence of a sphincter complex [21].…”

Section: Clamping Devicesmentioning

confidence: 99%

Fecal Incontinence: From Anatomy to Recent Advances

Chalise,

Bhattacharya,

P. Kandel

2023

Anorectal Disorders - From Diagnosis to Treatment

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The anatomy and physiology of the pelvic floor are complex. A thorough understanding of the anatomy is required to understand how we attain physiological continence. Fecal incontinence can be a life-altering condition that presents as an inability to maintain voluntary control of the passage of gas, liquid, or solid stool through the anus in patients who previously had control. The key to successfully managing a patient with fecal incontinence is to identify the underlying cause. There have been many prescribed procedures for patients requiring surgical correction to attain continence. However, the results are dismal for many patients. Recent advances have challenged these procedures with higher success rates.

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An artificial anal sphincter based on a novel clamping mechanism: Design, analysis, and testing

Cited by 7 publications

References 25 publications

Artificial sphincters: An overview from existing devices to novel technologies

Artificial sphincters: An overview from existing devices to novel technologies

Design and evaluation of perception reconstruction with sensor system for artificial anal sphincter based on vector similarity

Fecal Incontinence: From Anatomy to Recent Advances

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