An effective dual sensor for Cu2+ and Zn2+ with long-wavelength fluorescence in aqueous media based on biphenylacrylonitrile Schiff-base

A benzimidazole-derived fluorescent chemosensor for Cu(ii)-selective turn-off and Zn(ii)-selective ratiometric turn-on detection in aqueous solutions

“…However, it was also noted that the imbalance of Zn 2+ and Cu 2+ concentrations could lead to various diseases, such as metabolic disorders, Parkinson's disease, coronary heart disease, etc. [7][8][9][10]. Hence, it is of great significance to develop highly selective and sensitive fluorescent chemosensor to quantitatively detect Cu 2+ and Zn 2+ in biological and environmental fields.…”

“…Hence, it is of great significance to develop highly selective and sensitive fluorescent chemosensor to quantitatively detect Cu 2+ and Zn 2+ in biological and environmental fields. In this regard, fluorescent sensors for Cu 2+ and Zn 2+ detection have been designed based on various coordination scaffolds [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27]. For example, a naphthalene Schiff-base has been designed as a fluorescent sensor for Cu 2+ and Zn 2+ , where the fluorecence of sensor was quenched by Cu 2+ or enhanced by Zn 2+ over other metal cations in DMSO, respectively [11].…”

“…5,6 However, it has also been noted that an imbalance of Zn 2+ and Cu 2+ concentrations can lead to various diseases, such as metabolic disorders, Parkinson's disease, and coronary heart disease. [7][8][9][10] Hence, it would be of great significance to develop a highly selective and sensitive fluorescent chemosensor to quantitatively detect Cu 2+ and Zn 2+ in biological and environmental fields. In this regard, a number of fluorescent sensors for Cu 2+ and Zn 2+ detection have been designed based on various coordination scaffolds.…”

“…In this regard, a number of fluorescent sensors for Cu 2+ and Zn 2+ detection have been designed based on various coordination scaffolds. [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] For example, a naphthalene Schiff-base system was designed as a fluorescent sensor for Cu 2+ and Zn 2+ , where the fluorescence of the sensor was quenched by Cu 2+ or enhanced by Zn 2+ over other metal cations in DMSO, respectively. 11 Kim et al reported a phenanthrene-based multifunctional chemosensor that showed a slightly enhanced and blue-shifted (45 nm) fluorescence emission in the presence of Zn 2+ , whereas Cu 2+ caused a serious quenching of the original fluorescence.…”

Synthesis, “turn-on” fluorescence signals towards Zn2+ and Hg2+ and monoamine oxidase A inhibitory activity using a molecular docking approach of morpholine analogue Schiff base linked organosilanes

“…31,32 They are considered to be the ' best ligands ' for use as chelating agents, catalysts and corrosion inhibitors. [33][34][35] Furthermore, Schiff bases having morpholine moieties are more stable in biological systems and hence show improved biological activities such as antimicrobial, anti-oxidant, antidiabetic, antiinflammatory, analgesic, anaesthetic, HIV-protease inhibition, anti-tuberculosis. 36,37 Another significant family of heterocyclic compounds is the 1,2,3-triazoles, which are synthesized by Cu(I)-catalyzed azidealkyne cycloaddition.…”