An efficient and green synthesis of 1,4-dihydropyridine derivatives through multi-component reaction in subcritical EtOH

1,4-Dihydropyridine: synthetic advances, medicinal and insecticidal properties

“…This study is signicant since it takes less time, uses a traditional work-up, and does not use column chromatography. 31 Radioactive 13 N-labeling experiments were carried out by Blower et al (2021). The ndings were interesting and are quite useful for the radiochemical synthesis of [ 13 N] 1,4-DHP 14 derivatives using several benzaldehydes 14a and b-keto ester 14b in the presence of radiolabeling ammonia 14c (Scheme 15).…”

“…This study is significant since it takes less time, uses a traditional work-up, and does not use column chromatography. 31 …”

Aggregation-induced emission (AIE) from poly(1,4-dihydropyridine)s synthesized by Hantzsch polymerization and their specific detection of Fe2+ ions

“…The Hantzsch reaction is a common multi-component reaction used in organic chemistry. 22,23 In recent years, this reaction has been introduced into the field of polymer chemistry and has gained wide interest. [24][25][26][27][28][29] In theory, when a diamine and dialdehyde are selected as the components in a Hantzsch reaction system, Hantzsch polymerization can take place, and the resulting poly(1,4-dihydropyridine) derivatives (PDPEs) can be prepared.…”