An Efficient Route for the Synthesis of 11‐Aroyldiindeno[1,2‐b:2′,1′‐e]pyridine‐10,12‐diones

Abstract

A series of novel 11‐aroyldiindeno[1,2‐b:2′,1′‐e]pyridine‐10,12‐dione derivatives were synthesized, in good to excellent yields and short reaction times via one‐pot, three‐component reactions between indan‐1,3‐dione, ammonium acetate, and arylglyoxal hydrates in the presence of solid p‐toluenesulfonic acid.

One-pot, three-component synthesis of pyrrolo[2,3-d]pyrimidine derivatives

“…In attempting to develop a simple, one-pot and short reaction pathway for the synthesis of various heterocyclic compounds, we reported earlier the synthesis of pyrazolo [3,4-d]pyridines, pyrazolo[3,4-b]qunolin-5-ones and pyrazolo [4',3':5,6] 2,3,4,5,8-hexahydropyrido[2,3d]pyrimidine -6-carbonitriles, pyrrolo[3,2-d]pyrimidines [17][18][19][20][21][22][23].…”

“…In continuation of our interest in the synthesis of new heterocyclic compounds via one-pot, multicomponent reactions [17][18][19][20][21][22][23], herein we report a convenient and rapid method for the synthesis of pyrrolo[2,3-d]pyrimidine derivatives by one-pot three-component reactions using arylglyoxals 1a-d, 6-amino-1,3-dimethyluracil (2) and barbituric acid derivatives 3a-c in the presence of a catalytic amount of TBAB (5 mol%) at 50 °C in ethanol.…”

One‐pot, three‐component synthesis of polyfunctionalized benzo[h]pyrazolo[3,4‐b][1,6]naphthyridine and benzo[g]pyrazolo[3,4‐b]quinoline derivatives in the presence of silver nanoparticles (AgNPs)

“…In continuation of our previous studies on the application of aryl glyoxals in the synthesis of heterocyclic compounds, [ 22–29 ] herein, we report a one‐pot, three‐component reaction of aryl glyoxal monohydrates, 5‐amino‐1‐aryl‐3‐methylpyrazoles, and 4‐hydroxyquinoline‐2(1 H )‐one or 2‐hydroxy‐1,4‐naphthoquinone (lawsone) using AgNPs as nanocatalyst in H 2 O/EtOH under mild conditions to afford the corresponding pyrazolonaphthyridines and pyrazoloquinolines, respectively, in good to high yields.…”

A Facile Synthesis of Xanthene‐1,8(2H)‐dione Derivatives by Using Tetrapropylammonium Bromide as Catalyst

“…In continuation of our interest in the development of highly expedient methods for the synthesis of various heterocyclic compounds with potential pharmaceutical and biological properties , herein we report a synthetic route for the synthesis of a new series of xanthene‐1,8(2 H )‐dione derivatives via the condensation reaction of arylglyoxals 1 with 1,3‐diketones 2 , such as cyclohexane‐1,3‐dione or dimedone, and TPAB in the presence of ethanol/water under reflux conditions, in high to excellent yields.…”