Three amino alkylated indoles are efficiently synthesized in one pot three component reaction under microwave irradiation. Magnesium ferrite (MgFe2O4) nanoparticles 10 mole% has been used as heterogeneous catalyst which may easily be recovered by application external magnet and recovered catalyst can be reused at least for five runs without affecting the efficiency of the catalyst. The solvent free protocol developed has advantage of less reaction time required, high yields, easy work up and protocol is applicable to various acid base sensitive functional groups present in the substrate. The reported methodology is highly suitable especially for primary amines in addition to secondary amines as one of the components.