An efficient solventless synthesis of cycloalkeno-1,2,3-selenadiazoles, their antimicrobial studies, and comparison with parent semicarbazones

Jadhav, Aditi A.; Dhanwe, Vaishali P.; Joshi, Prasad G.; Khanna, Pawan K.

doi:10.1007/s10593-015-1666-9

Cited by 22 publications

(3 citation statements)

References 18 publications

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“…Complex formation of semicarbazones with Cu (II) enhances the rate of membrane perforation as well as cell membrane disruption. Hence, Cu (II) complexes are more effective as compared to their ligands . Cu (II) ions show no significant effect on the bacterial growth as they fail to cross the lipid rich cell membrane of E. coli .…”

Section: Resultsmentioning

confidence: 99%

Synthesis, Characterization and Nanochemistry of Novel Antibacterial Copper (II) Semicarbazone Complexes

et al. 2018

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First report on copper (II) complexes (Cu (II)) of unsubstituted cyclic aliphatic semicarbazones is presented. Copper (II) complexes with semicarbazone derivatives of cyclopentanone (C5), cyclohexanone (C6), cycloheptanone (C7) and cyclooctanone (C8) are synthesized and characterized by physico‐chemical techniques such as melting point, Ultra Violet‐Visible, Diffuse Reflectance (UV‐Vis‐DRS), Fourier Transform Infra Red (FTIR), FT‐Raman, proton nuclear magnetic resonance (1HNMR) spectroscopy and Mass spectrometry. The electrochemical behavior of the complexes was studied using cyclic voltammetry revealing Cu (II) to Cu (I) redox couple. The molar conductance study of copper complexes showed non‐electrolytic nature. As‐synthesized ligands and their complexes were evaluated against gram ‐ve bacteria Escherichia coli. The antibacterial results of the ligands and complexes were compared. The copper complexes were found more effective against bacterial growth than ligands. As‐synthesized cyclooctanone copper complex (CC8) was successfully employed as precursor for synthesis of copper oxide nanoparticles and its fromation was confirmed by UV‐Visible spectroscopy and XRD analysis.

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Section: Resultsmentioning

confidence: 99%

Synthesis, Characterization and Nanochemistry of Novel Antibacterial Copper (II) Semicarbazone Complexes

et al. 2018

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“…In recent years, the development of new sustainable methodologies has gained the attention of the scientific community, leading to the application of environmentally benign synthetic procedures. [11] Organochalcogen compounds are gaining increasing interest in the area of synthesis, mainly because of their impressive potential application in the biological sciences, [12] as anticancer, [13][14][15][16] anti-Alzheimer, [17][18][19][20] antimicrobial, [21][22][23] antiviral, [24][25][26] anti-inflammatory, [27][28][29] anti-diabetic, [30][31][32] and antidepressant agents, [33][34][35] among other uses. [36][37][38] They also play a significant role in modern organic synthesis and materials science.…”

Section: Introductionmentioning

confidence: 99%

“…Organochalcogen compounds are gaining increasing interest in the area of synthesis, mainly because of their impressive potential application in the biological sciences, as anti‐cancer, anti‐Alzheimer, antimicrobial, antiviral, anti‐inflammatory, anti‐diabetic, and antidepressant agents, among other uses . They also play a significant role in modern organic synthesis and materials science .…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Electrochemical Chalcogen (S/Se)‐Functionalization of Organic Molecules

et al. 2019

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Achieving advances in the development of clean and efficient synthetic routes has become an important aim in research. In recent years, the search for new sustainable methodologies, notably environmentally benign synthetic procedures, has gained the attention of the scientific community. Electrosynthesis is a tool that has been extensively studied due to its potential application in chemical transformations and it adheres to the principles of green chemistry. Organochalogen compounds form an important class of molecules, since many of them have properties that can be applied in medicine and materials science. Thus, herein we provide a comprehensive and updated overview covering recent advances in the electrochemical C(sp2)−H bond chalcogenation of activated arenes and heterocycles as well as electrochemical chalcogenation through oxidative cross‐coupling reactions and chalcogen‐functionalization of alkenes/alkynes. The scope, limitations, and mechanisms are described and discussed, detailing the fundamental aspects and benefits of electrochemistry for the chalcogenation of organic compounds. The content of this Minireview demonstrates that it is possible to provide new synthetic routes and to improve the existing methodologies, to obtain processes more in line with current environmental protection aims. The reader will also find a discussion on the fundamental aspects and benefits of applying electrosynthesis to the assembly and operation of an electrolytic cell.

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ChemInform Abstract: An Efficient Solventless Synthesis of Cycloalkeno‐1,2,3‐selenadiazoles, Their Antimicrobial Studies, and Comparison with Parent Semicarbazones.

et al. 2015

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An efficient solventless synthesis of cycloalkeno-1,2,3-selenadiazoles, their antimicrobial studies, and comparison with parent semicarbazones

Cited by 22 publications

References 18 publications

Synthesis, Characterization and Nanochemistry of Novel Antibacterial Copper (II) Semicarbazone Complexes

Synthesis, Characterization and Nanochemistry of Novel Antibacterial Copper (II) Semicarbazone Complexes

Recent Advances in Electrochemical Chalcogen (S/Se)‐Functionalization of Organic Molecules

ChemInform Abstract: An Efficient Solventless Synthesis of Cycloalkeno‐1,2,3‐selenadiazoles, Their Antimicrobial Studies, and Comparison with Parent Semicarbazones.

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