2023
DOI: 10.1002/slct.202204644
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An Efficient Synthesis of Rivaroxaban

Abstract: An efficient synthesis of rivaroxaban has been accomplished by a sequence spanning five steps from 4-morpholinoaniline and (S)-2-(oxiran-2-ylmethyl)isoindoline-1,3-dione with an overall yield of 44 %. This synthesis is concise, environmentally benign and cost-effective, providing a good basis for the development of a new process for rivaroxaban.

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Cited by 1 publication
(1 citation statement)
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“…[19,20] Of particular note is CuO NPs' favorable band gap of approximately 2.6 eV, rendering them valuable in applications involving solar energy conversion, solar cell window materials, and visible-light photocatalysis. [21] Recent studies have further underscored the potential of CuO NPs in diverse areas, including drug delivery systems, [22,23] environmental remediation, [24,25] and catalysis, [26,27] making them a promising material for multifaceted applications.…”
Section: Introductionmentioning
confidence: 99%
“…[19,20] Of particular note is CuO NPs' favorable band gap of approximately 2.6 eV, rendering them valuable in applications involving solar energy conversion, solar cell window materials, and visible-light photocatalysis. [21] Recent studies have further underscored the potential of CuO NPs in diverse areas, including drug delivery systems, [22,23] environmental remediation, [24,25] and catalysis, [26,27] making them a promising material for multifaceted applications.…”
Section: Introductionmentioning
confidence: 99%