Herein, an electrochemical sensor for the detection of H 2 O 2 based on nafion glassy carbon electrode modified with MIL101(Cr) and nano-MIL101(Cr) are developed and its electrochemical characterizations analyzed by CV and CA. In comparison with the NGCE, MIL101/NGCE and nano-MIL101/NGCE, the nano-MIL101/NGCE showed a sharp redox peak specific to H 2 O 2 was obtained in the phosphate-calibrated solution.nano-MIL101/NGCE exhibited good linear response in terms of the relationship between peak currents and concentrations as from 0 to 650 μM (R 2 = 0.99), with a low limit of detection 3.8 μM, high sensitivity 986 μA mM À 1 cm À 2 and nano-MIL101/NGCE exhibited ideal repeatability, reproducibility, stability and the interference-free perception of H 2 O 2 .