An Electrochemical Electrode to Detect Theophylline Based on Copper Oxide Nanoparticles Composited with Graphene Oxide

Patil, Vinoda B.; Malode, Shweta J.; Mangasuli, Sumitra N.; Tuwar, Suresh M.; Mondal, Kunal; Shetti, Nagaraj P.

doi:10.3390/mi13081166

Cited by 30 publications

(12 citation statements)

References 51 publications

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“…As some other authors have reported, a variety of excipients including cellulose, starch, talc, titanium dioxide, sodium lauryl sulfate, lactose, among others, do not interfere with the electrochemical signal of different APIs using different carbon-based working electrodes, even at excipient concentrations ranging from 60 to 100 times higher than the API. [45][46][47][48][49] Likewise, for the electrochemical study of PAR from different authors, no excipient interference was observed. [50][51][52] Since the modified electrodes will be in a solution at 37…”

Section: Interferents Study Electrode Stress Test and Surface Saturationmentioning

confidence: 89%

Carbon Nanotube Modified Glassy Carbon Electrodes for on‐line and off‐line in vitro Therapeutic Equivalence Assessment of Paracetamol Tablets

Cumsille‐Escandar,

Yáñez,

Álvarez‐Lueje

2024

ChemistrySelect

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In vitro bioequivalence assessment of paracetamol tablets was carried out by differential pulse voltammetry (DPV) and amperometry using a multiwalled carbon nanotube modified glassy carbon electrode (GCE/MWCNT). For the DPV developed method, samples were collected from the USP paddle apparatus, while amperometric measurements were carried out in situ. The DPV method was validated in three supporting electrolytes (per in vitro bioequivalence guidelines) by measuring the recovery from standard solutions and paracetamol tablet solutions, while precision was evaluated through the RSD (n=6). In HCl pH 1.2 solution the LOD and LOQ were 48 nM and 160 nM, respectively and the linear range was between 0.18–2.2 μM. In acetate buffer pH 4.5 the LOD and LOQ were 15 nM and 51 nM, respectively and the linear range was between 88 nM–880 nM. And in phosphate buffer pH 6.8 the LOD and LOQ were 4.6 nM and 15 nM, respectively and the linear range was between 88 nM–880 nM. Recovery values were between 95 and 105 % and precision values were less than 5 %. Results showed that both methods were effectively applied for the analysis of samples.

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Section: Interferents Study Electrode Stress Test and Surface Saturationmentioning

confidence: 89%

Carbon Nanotube Modified Glassy Carbon Electrodes for on‐line and off‐line in vitro Therapeutic Equivalence Assessment of Paracetamol Tablets

Cumsille‐Escandar,

Yáñez,

Álvarez‐Lueje

2024

ChemistrySelect

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“…The unique qualities of hybrid nanoparticles, which can typically not be maintained by a single type of nanoparticle, are imparted by the definitively structured and organized nanocomposites of two or more different nanoparticles . One medication delivery method called composite nanoparticles frequently combines two or more distinct drug carriers, each with a constant dimension in the nanoscale, from the perspective of drug delivery and biological applications. − They can be made up of a fusion of two or more inorganic components, organic components, or a combination of both . The final nanocomposite is a blend of a substance with unique synergistic qualities.…”

Section: Introductionmentioning

confidence: 99%

Carbon Nanomaterials for Biomedical Applications: Progress and Outlook

Malode,

Pandiaraj,

Alodhayb

et al. 2024

ACS Appl. Bio Mater.

Self Cite

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Recent developments in nanoscale materials have found extensive use in various fields, especially in the biomedical industry. Several substantial obstacles must be overcome, particularly those related to nanostructured materials in biomedicine, before they can be used in therapeutic applications. Significant concerns in biomedicine include biological processes, adaptability, toxic effects, and nano-biointerfacial properties. Biomedical researchers have difficulty choosing suitable materials for drug carriers, cancer treatment, and antiviral uses. Carbon nanomaterials are among the various nanoparticle forms that are continually receiving interest for biomedical applications. They are suitable materials owing to their distinctive physical and chemical properties, such as electrical, high-temperature, mechanical, and optical diversification. An individualized, controlled, dependable, low-carcinogenic, target-specific drug delivery system can diagnose and treat infections in biomedical applications. The variety of carbon materials at the nanoscale is remarkable. Allotropes and other forms of the same element, carbon, are represented in nanoscale dimensions. These show promise for a wide range of applications. Carbon nanostructured materials with exceptional mechanical, electrical, and thermal properties include graphene and carbon nanotubes. They can potentially revolutionize industries, including electronics, energy, and medicine. Ongoing investigation and expansion efforts continue to unlock possibilities for these materials, making them a key player in shaping the future of advanced technology. Carbon nanostructured materials explore the potential positive effects of reducing the greenhouse effect. The current state of nanostructured materials in the biomedical sector is covered in this review, along with their synthesis techniques and potential uses.

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“…The interdigitated electrode is patterned on either of these boards by chemical etching using FeCl 3 , and then the hybrid is spin coated over it. The sensing property can be studied by using the Keithley Source/Measure unit (SMU). – …”

Section: Introductionmentioning

confidence: 99%

GO/CuO Nanohybrid-Based Carbon Dioxide Gas Sensors with an Arduino Detection Unit

Bhat,

Ukkund,

Ashraf

et al. 2023

ACS Omega

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A gas sensor is a device that detects the presence of gases in a specific area. This research work demonstrates the effectiveness of gas sensors based on graphene oxide (GO) and copper oxide (CuO) semiconductor nanomaterials for the detection of carbon dioxide. GO and CuO were prepared by the modified Hummer’s method and precipitation method using CuCl 2 as a precursor, respectively. These materials are made into a hybrid using poly(vinyl alcohol) (PVA)/poly(vinylpyrrolidone) (PVP) polymer solutions of low concentrations and are spin coated onto the pattern-etched copper-clad substrate. The sensor is tested using a source measurement unit (SMU) to obtain the change in the resistance of the sensor in open air and in a carbon dioxide environment. The fabricated sensor with an Arduino microcontroller detection unit showed a good sensing response of 60%.

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An Electrochemical Electrode to Detect Theophylline Based on Copper Oxide Nanoparticles Composited with Graphene Oxide

Cited by 30 publications

References 51 publications

Carbon Nanotube Modified Glassy Carbon Electrodes for on‐line and off‐line in vitro Therapeutic Equivalence Assessment of Paracetamol Tablets

Carbon Nanotube Modified Glassy Carbon Electrodes for on‐line and off‐line in vitro Therapeutic Equivalence Assessment of Paracetamol Tablets

Carbon Nanomaterials for Biomedical Applications: Progress and Outlook

GO/CuO Nanohybrid-Based Carbon Dioxide Gas Sensors with an Arduino Detection Unit

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