During the past few decades, there have been different studies on e-business but there are limited numbers of works accomplished on measuring the impact of e-business on supply chain. Although e-business may not directly influence on organizational performance, it can have significant indirect impact on unifying customers and suppliers, which yields to a better performance of organizations. In this study, we perform an empirical study to measure the indirect impact of e-business on organizational performance. The proposed study of this paper designs a questionnaire and distributes it among 40 professional experts in various industries in province of Ilam, Iran. The survey examines four hypothesis for a possible correlation between e-business and integrated suppliers, e-business and customers, integrated customers and suppliers with organizational performance. The results of this survey confirm a positive relationship between all these components either directly or indirectly.