An Evidence-Based Systematic Review of Green-Lipped Mussel (Perna canaliculus) by the Natural Standard Research Collaboration

Abstract

A blinded review is conducted by multidisciplinary research-clinical faculty at major academic centers with expertise in epidemiology and biostatistics, pharmacology, toxicology, CAM research, and clinical practice. In cases of editorial disagreement, a three-member panel of the Editorial Board addresses conflicts, and consults experts when applicable. Authors of studies are contacted when clarification is required.

Adverse effects of herbal medicines: an overview of systematic reviews

“…Full-text articles assessed for eligibility (n =184) 37,54 perinatal stroke, acute myocardial infarction, congestive heart failure, 54 severe multiorgan hypoxic injury, 22 carcinoma, 33,61 perforation of the gastrointestinal tract, 61 seizures and epilepsy. 58 The large number of included SRs means that it is not easy to provide practical guidance through this labyrinth of HMs and multitude of AEs.…”

“…26 Thirty-one SRs concluded that the HM in question was safe. [13][14][15][16][17][18][19][20][21][23][24][25][26]29,31,32,35,38,39,[42][43][44][45]47,50,53,55,[57][58][59][60] Fifteen SRs reported moderately severe AEs, 12,22,27,28,30,36,40,41,46,48,49,51,52,54,56 and four SRs concluded that the HM in question was not safe (see Supplemental Tables S1 and S2). 33,34,37,…”

“…Forty-two SRs failed to mention conflict of interest of the authors. [13][14][15][16][17][18]22,23,[25][26][27][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61] Thirty-two SRs made no mention of any source of funding. [13][14][15][16][17]22,23,27,30,[34]…”

“…[13][14][15][16][17]21,23,27,[32][33][34][35][36][37][38][39][40]45,47,[50][51][52][53][54][55][56][57][58][59][60][61] The number of primary studies included in the SRs ranged from 1 38 to 216. 28 The types of primary reports varied from case studies to epidemiological investigations.…”

Changes in proximate composition, lipid class and fatty acid profile in Greenshell™ mussels (Perna canaliculus) over an annual cycle

“…osteoarthritis/rheumatoid arthritis and asthma are well covered in a series of reviews(Brien, Prescott, Coghlan, Bashir, & Lewith, 2008;Cobb & Ernst, 2006;Coulson, Palacios, & Vitetta, 2015;Grienke, Silke, & Tasdemir, 2014;Ulbricht et al, 2009). Presently, there are no stud-…”