An expedient one-pot tandem method for the synthesis of 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-ones under green conditions

Kavitha, K.; Srikrishna, Devulapally; Dubey, P. K.; Aparna, P.

doi:10.1007/s13738-019-01661-y

Cited by 4 publications

(2 citation statements)

References 32 publications

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“…T A B L E 3 Outline for green solvent-mediated synthesis of thiazole derivatives. [77] 2 -Ethanol 80 12 h 82 [78] 3 Nanochitosan Ethanol Reflux 2.5-4.5 h 75-97 [79] 4 Sulfamic acid Water Reflux 3-6 h 64-89 [80] 5 -Ethanol Reflux 6 h 90-95 [81] 6 F e 3 O 4 @SiO 2 @KIT-6 Water RT 1-2 h 85-97 [82] 7 -PEG-600 RT 4 h 87 [83] 8 K 3 [Fe(CN) 6 ] Ethanol and KOH RT 2 h 80 [84] 9 -Water 90 20 h 65-85 [85] 10 CTAB Glycerol 40 1-3 h 82-96 [86] 11 Fe 3 O 4 @vitamin B 1 Water 80 30-45 min 79-93 [87] 12 -PEG-400 100 2-3.5 h 87-96 [88] 13 GAA PEG-300 70-75 1-1.5 h 82-96 [89] 14 -Water 135 35 min 50-89 [90] 15 Pyridine Water 150 20 h 40-84 [91] 16 -Water 60 1-6 h 65-90 [92] 17 -Glycerin RT 1-2.5 h 87-92 [93] 18 Ca/4-MePy-IL@ZY-Fe 2 O 3 and TCCA Ethanol 80 25 min 85-92 [94] 19 γ-Fe 2 O 3 @HAp@CPTMS@AT@Cu(ӀI) Ethanol RT 20-28 min 88-95 [95] 20 -Ethanol and water RT 60 min 90-98 [96] 21 Citric acid Ethanol and water Reflux 15-40 min 0-96 [97] 22 -Water Reflux 6 h 84-93 [98] 23 ZnO NP Ethanol/neat RT 2-8 min 90-99 [99] 24 PTSA PEG-400 80 2 h 79-95 [100] 25 Fe 2 O 3 NP Water RT 10-32 min 77-90 [101] 26 2-Hydroxypropyl-β-cyclodextrin Water and acetone 50 6 h 41-70 [102] 27 GAA PEG-400 70-75 1-5 h 80-95 [103] 28 Triton X-100 Water RT 5-10 min 85-98 [104] Abbreviations: CTAB, cetyl trimethyl ammonium bromide; GAA, glacial acetic acid; PEG, polyethylene glycol; PTSA, p-toluenesulfonic acid; TCCA, trichloroisocyanuric acid.…”

Section: S C H E M E 58mentioning

confidence: 99%

“…Kavitha et al [ 83 ] set forth a one‐pot synthesis of 2‐[2‐(phenylamino)thiazol‐4‐yl]acetate from ethyl‐4‐chloroacetoacetate and phenylthiourea in the presence phase transfer catalyst (PTC) such as PEG‐600 at ambient temperature for 4 h to obtain the excellent product (87%). Additionally, PEG is a hydrophilic polymer and has been suggested as a solvents for organic processes (Scheme 42).…”

Section: Green Synthetic Approach For the Synthesis Of Thiazole Deriv...mentioning

confidence: 99%

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Emerging green synthetic routes for thiazole and its derivatives: Current perspectives

Patel,

Bambharoliya,

Shah

et al. 2023

Archiv der Pharmazie

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This review article provides an overview of the green synthesis of thiazole derivatives, emphasizing sustainable and environmentally friendly methodologies. Thiazole derivatives possess significant value and find diverse applications across various fields. However, conventional synthesis methods often involve hazardous reagents and generate substantial waste, posing environmental concerns. The green synthesis of thiazole derivatives employs renewable starting materials, nontoxic catalysts, and mild reaction conditions to minimize environmental impact. Innovative techniques such as microwave irradiation, ultrasound synthesis, green solvents, a green catalyst‐based approach, and mechanochemistry‐mediated synthesis are employed, offering advantages in terms of scalability, cost‐effectiveness, and purification simplicity. The resulting thiazole derivatives exhibit comparable or enhanced biological activities, showcasing the feasibility and practicality of green synthesis in drug discovery. This review paper underscores the importance of sustainable approaches in functional molecular synthesis and encourages further research in this domain.

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