Offshore wind turbine (WT) wake interference will reduce power generation and increase the fatigue loads of downstream WTs. Wake interference detection based on aeroacoustic noise is believed to solve these challenges in offshore wind farms. However, aeroacoustic noise is closely related to the aerodynamics around WT blades, and the acoustic detection method requires the mastery of noise emission characteristics. In this paper, FAST.Farm, combined with the acoustic model in OpenFAST, is utilized to investigate the acoustic noise emission characteristics from two 3.4 MW-130 WTs with wake interference. Multi-microphone positions were investigated for the optimal reception selection under 8 m/s and 12 m/s wind speeds with a typical offshore atmospheric turbulence intensity of 6%. The numerical simulation results indicate that wake deficit reduces the total noise emission by about 6 dBA in the overall sound pressure level (OASPL) at 8 m/s, while wake turbulence marginally increases it and its fluctuation. There is a mutual influence between these effects, and the wake deficit effect can be 100% compensated for in the OASPL at 12 m/s. Additionally, downstream observer locations are suggested based on comparisons. These investigations provide new insights into wake interference in offshore wind farms.